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99% purity Propranolol hydrochloride 318-98-9 Medicine Raw Materials white powder

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99% purity Propranolol hydrochloride 318-98-9 Medicine Raw Materials white powder

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Product Details:

Place of Origin:	China
Brand Name:	DKY
Model Number:	318-98-9

Payment & Shipping Terms:

Minimum Order Quantity:	1kg
Packaging Details:	1kg/bag or 25kg/drum
Delivery Time:	5-7 work days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	30 tons per year

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Detailed Product Description

CAS No:	318-98-9	Molecular Formula:	C16H22ClNO2
Molecular Weight:	295.8	EINECS No:	206-268-7
Melting Point:	163-165 °C	Flash:	9 ℃
Solubility:	Soluble In Methanol, Slightly Soluble In Water, Glacial Acetic Acid And Ethanol, Slightly Soluble In Chloroform, Extremely Insoluble In Ethyl Ether, Benzene And Ethyl Acetate.	Appearance:	White Or Milky Crystalline Powder, Odorless.
High Light:	raw materials for drugs , medicine chemicals

99% purity Propranolol hydrochloride 318-98-9 Medicine Raw Materials white powder

Basic parameter:

1. Product name: Propranololhydrochloride

2. Product alias: PropranololHydrochlorideForPerformanc; 1 - ((1 - methylethyl) amino) - 3 - (1 - naphthalenyloxy) - 2 - propanohydrochloride; 1 - (1 - naphthyloxy) - 2 - hydroxy - 3 - isopropylaminopropanehydrochloride; 1 - (isopropylamino) - 3 - (1 - naphthyloxy) - 2 - propanohydrochloride; 1 - (isopropylamino) - 3 - (1 - naphthyloxy) propan - 2 - olhydrochloride; 1 - (isopropylamino) - 3 - (alpha - naphthoxy) - 2 - propanolhydrochloride; 1 - isopropylamino - 3 - (1 - naphthoxy) - propan - 2 - ol - hydrochloride; anaprilin

3. CAS no. : 318-98-9

4. Molecular formula: C16H22ClNO2

5. Molecular weight: 295.8

6. EINECS no. : 206-268-7

7. Melting point: 163-165 °C(lit.)

8. Flash: 9 ℃

9. Storage conditions: 2-8°C

10. Solubility: H2O: 50 mg/mL, clear, colorless

11. Appearance: white or milky crystalline powder, odorless.

12. Solubility: soluble in methanol, slightly soluble in water, glacial acetic acid and ethanol, slightly soluble in chloroform, extremely insoluble in ethyl ether, benzene and ethyl acetate.

Certificate of Analysis:

Product Name:PROPRANOLOL HCL
Batch NO	20190918	BW	500KG
Manufaturing Date	2019/09/16	Expiry Date	2021/09/15
Molccular Fonnular	C₁₆H₂₂ClNO₂	Moleculgr Weight	295.81

ITEM	STANDARD	ANALYSED RESULT
Description	White crystalline powder	Comform
Rotation	-1.0°~+1.0°	+0.08°
Identification
A	Infra-red absorption spectrum should be identical with contrast spectrum	Comform
B	Major peak retention time of Assay preparationis orresponds to that of Standard preparation	Comform
C	Should be posotive reaction	Comform
Inspect
Melting range	162℃~165℃	163~164.5℃
PH(25℃)	5.0~6.0	5.5
Acidity or alkalinity	Comform	Comform
Clarity and colour of solution	Comform	Comform
Heavy metals	Comform	Comform
Solubility	Soluble in 1%w/v water	Comform
Loss on drying	NMT0.5%	0.09%
Sulphated ash	NMT0.1%	0.05%
Related substance
Total impurities	≤0.4%	0.25%
Single substances	≤0.1%	0.06%
Residual solwents & Volatile Organic Impurities
Chloroform	≤60PPM	Comform
1,4-Dioxane	≤380PPM	Comform
Methylene Chloride	≤600PPM	Comform
Tapped Density	≥0.5g/ml	Comform
Trichloroethylene	≤80PPM	Comform
Assay	99.0-101.0%	99.6%
Granulometry(100mesh)	≥70%	Comform
Conclusion	Conform to BP2010 USP32

Structure:

Indications:

1. Reduce mortality from myocardial infarction as secondary prevention.

2. Hypertension (alone or in combination with other antihypertensive drugs.

3. Labor angina.

4. Control ventricular tachyarrhythmia, ventricular arrhythmia, especially arrhythmias related to catecholamine or digitalis. It can be used for the control of ventricular events in patients with digitalis and atrial fibrillation, and can also be used for intractable presystole to improve the symptoms of patients.

5. Reduce the outflow pressure difference of hypertrophic cardiomyopathy, relieve the symptoms of angina pectoris, palpitations and fainting.

6. With lebenium blocker for controlling tachycardia in patients with pheochromocytoma.

7. It is used to control the rapid heart rate in hyperthyroidism, and can also be used in the treatment of thyroid crisis.

USES: for all kinds of functional arrhythmias, supraventricular and ventricular ectopic contractions, atrial fibrillation and arrhythmias caused by anesthesia.

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