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Chloroquine Diphosphate Pharmaceutical Raw Material 50-63-5 For Treatment Covid-19

Chloroquine Diphosphate Pharmaceutical Raw Material 50-63-5 For Treatment Covid-19

Chloroquine Diphosphate Pharmaceutical Raw Material 50-63-5 For Treatment Covid-19
Chloroquine Diphosphate Pharmaceutical Raw Material 50-63-5 For Treatment Covid-19

Large Image :  Chloroquine Diphosphate Pharmaceutical Raw Material 50-63-5 For Treatment Covid-19 Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: 50-63-5

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Price: $70-90/kg
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 3-5 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 200 tons per year
Detailed Product Description
CAS Number: 50-63-5 Molecular Formula: C18H32ClN3O8P2
Molecular Weight: 515.86 EINECS No: 200-055-2
Melting Point: 193~196℃, Simultaneous Decomposition During Melting Boiling Point: 460.6ºC At 760 MmHg
Flash: 232.3ºC Storage Conditions: Desiccate At RT
Solubility: H2O: 50 Mg/mL, Clear Water Solubility: Water Soluble, In Ethanol, Chloroform, Ether Almost Insoluble
Appearance: White Crystalline Powder; Odourless; Light Gradient; The Aqueous Solution Reacts With Acidity. Storage: Shading And Sealing
High Light:

pharma raw material

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raw materials for medicines

Chloroquine diphosphate 50-63-5 pharmaceutical raw material for the treatment of covid-19
 
Basic parameter:
1. Product name: Chloroquine diphosphate
2. Nicknames :7-chloro-4-((4 '-diethylamino-1-methylbutyl)amino)quinolinediphosphate; 4 - (4-7 - chloro - diethylamino - 1 - methyl - butylamino) - quinolindiphosphate; Alermine; Aralendiphosphate; Chingaminphosphate; Chloroquindiphosphate; Chloroquinebis (phosphate); chloroquinebis
3. CAS number: 50-63-5
4. Molecular formula: C18H32ClN3O8P2
5. Molecular weight: 515.86
6. EINECS no. : 200-055-2
7. Melting point: 193~196℃, simultaneous decomposition during melting
8. Boiling point :460.6 C at 760 mmHg
9. Flash: DHS 232.3 C
10. Storage conditions :Desiccate at RT
11. Solubility :H2O: 50 mg/mL, clear
12. Water solubility: water soluble, in ethanol, chloroform, ether almost insoluble
13. Appearance: white crystalline powder; Odourless; Light gradient; The aqueous solution reacts with acidity.
14. Storage: shading and sealing
 
Certificate of Analysis:

Product Name

Chloroquine phosphate

(Packing) 25kg/drum

product grade

pharmaceutical

MFG. Date

04/2020 Quantity 1000kg

Sample Quantity

50g

Batch No.

20200403

Testing basis

 

USP32

Expiry Date

03/2024

Test Items

Testting standard

Testing Results

Description

White or almost white crystalline powder

complies

Identification

positive complies

Melting point

195℃ 193.5℃

Solutions

Comply with test

complies

 

Appearance of solution

<BY5 OR GY5 <GY5

PH(10%W/V)

 

3.8-4.3 4.2

Related substance

One spot <1.0% and any other spot<0.5%

complies

Water

<2.0% 1.8%

Heavy metals

<20ppm <10ppm

Assay

98.5%--101.0% 99.4%

Conclusion

Conform to the specification of USP32

 
Structure:
Chloroquine Diphosphate Pharmaceutical Raw Material 50-63-5 For Treatment Covid-19 0
 
Pharmacological effects:
Chloroquine phosphate has a strong binding force with the nuclear protein, and the negative 7-chloride group on its quinoline ring is close to the 2-amino group on DNA guanine, so that chloroquine is inserted between the two strands of DNA double helix. compounds with DNA, preventing DNA replication and RNA transcription. Chloroquine also inhibits the incorporation of phosphoric acid into the plasmodium's DNA and RNA, interfering with its reproduction due to a reduction in nucleic acid synthesis.
 
Summary:
Chloroquine phosphate is a 4-aminoquinoline antimalarial drug, which can inhibit the synthesis of nucleic acid of plasmodium fission, interfere with the growth and reproduction of plasmodium, and effectively kill plasmodium red internal fission.
 
Application:
Chloroquine phosphate can be used to treat falciparum, vivax and malariae malaria which are sensitive to chloroquine. It can also be used for the inhibition and prevention of malaria symptoms. It can also be used for the treatment of parenteral amoebiasis, connective tissue disease, photosensitive diseases (such as erythema), etc.

 

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Tel: 86-15377658509

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