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Cholestyramine 11041-12-6 pharmaceutical raw material white powder has a slight odor

Cholestyramine 11041-12-6 pharmaceutical raw material white powder has a slight odor

Cholestyramine 11041-12-6 pharmaceutical raw material white powder has a slight odor
Cholestyramine 11041-12-6 pharmaceutical raw material white powder has a slight odor

Large Image :  Cholestyramine 11041-12-6 pharmaceutical raw material white powder has a slight odor Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: 11041-12-6

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 50kg per year
Detailed Product Description
CAS No: 11041-12-6 Molecular Formula: C27H47N
Molecular Weight: 385.66878 EINECS No: 234-270-8
PH: 4.0 To 6.0 Storage Condition: Airtight Against Light, Dry And Ventilated.
Index Of Refraction: 1.62 Density: 1.24 G/cm3
Melting Point: 125 °C Water Solubility: Soluble
Flash: 204ºC Boiling Point: 413.7 C At 760 MmHg
Appearance: Light White To Light Yellow Crystal Or Crystalline Powder USES: Cholesterol-lowering Drugs, Used In Ⅱ Type Hyperlipidemia, Atherosclerosis And Other Diseases.
High Light:

pharma raw material

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raw materials for medicines

Cholestyramine 11041-12-6 pharmaceutical raw material white powder has a slight odor

 

Basic parameter:

1. Product name :CHOLESTYRAMINERESIN
2. Product alias :cholestyraminechloride; Colestyramin; Cuemid; Polystyrenebenzyltrimethylaminoniumchloride; Quantalan; DOWEX1X2CL - FORM; CHOLESTYRAMINE. CHOLESTYRAMINERESIN
3. CAS no. : 11041-12-6
4. Molecular formula: C27H47N
5. Molecular weight: 385.66878
6. EINECS no. : 234-270-8
7. PH: 4.0 to 6.0
8. Storage condition: airtight against light, dry and ventilated.
9. Index of refraction: 1.62
10. Density: 1.24 g/cm3
11. Melting point: 125 °C
12. Water solubility: soluble
13. Flash: 204 DHS C
14. Boiling point :413.7 C at 760 mmHg
15. USES: cholesterol-lowering drugs, used in Ⅱ type hyperlipidemia, atherosclerosis and other diseases.
16. Appearance: light white to light yellow crystal or crystalline powder
 
Certificate of Analysis:
Product Name Cholestyramine Batch No. 191021
Packing 25kg/drum Expiry Date Oct.20,2022
Inspection Sheet No. 20191021 Exp.Date Three Years
Report Date Oct.21.2019    
Standard Enterprise standard
Items Specification Results

[Characteristics]

 

 

[Identification]

 

 

[Test]

Acidity

Dialysis quaternary

Ammonium

Chloride

Loss on drying

Residue on ignition

Heavy metals

 

Exchange capacity

White or off-white powder,odorless or some

amine smell;Moisture absorption

 

IR absorption spectrogram comply with refercnce standard spectrogram

 

 

PH4.0-6.0

Complies

 

13.0-17.0%(On drying basis)

12.0%max

0.1%max

Complies

 

exchange sodium taurocholate per gram should be 2.0-2.4g on drying basis

 

off-white powder, some amine smell;Moisture absorption

 

Complies

 

 

 

4.2

Complies

 

16.1%

7.2%

Complies

Complies

 

2.2g

Conclusion:Enterprise standard

 

Product overview:
Cholestyramine is one of the most important class of resin drugs that have a lipid-lowering effect. The effect of the drug on lowering cholesterol and the morbidity and mortality of coronary heart disease has been confirmed by long-term and large-scale clinical practice. However, because it has certain side effects and its lipid-lowering effect is not as good as that of "statins", it has been rarely used in clinical practice in recent years. However, when used in combination with other lipid-lowering drugs, it can improve the efficacy and reduce the side effects, which has good clinical significance.
 
Indications:
Mainly used in the treatment of Ⅱ type a high lipoprotein hematic disease, especially in the familial hypercholesterolemia. In addition, it is also used for the treatment of primary biliary cirrhosis, pruritus of drug-induced cholestasis jaundice, hypercholesterolemia, chronic cholecystitis, gallstones, porphyria, etc. Treatment of atherosclerosis: 4~ 5g, 3 times /d. Antipruritic: the initial dosage is 6 ~ 10g/d, and the maintenance dosage is 3g/d, taken in 3 times. Long-term use can reduce the intestinal combined with bile salt, resulting in poor fat absorption. Long-term use should be appropriately supplemented with vitamin A, D, K and other fat-soluble vitamins and calcium. People with gastrointestinal reactions can appropriately add stomach strengthening drugs.
 
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