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Cholestyramine 11041-12-6 pharmaceutical raw material white powder has a slight odor

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Cholestyramine 11041-12-6 pharmaceutical raw material white powder has a slight odor

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Product Details:

Place of Origin:	China
Brand Name:	DKY
Model Number:	11041-12-6

Payment & Shipping Terms:

Minimum Order Quantity:	10g
Packaging Details:	1kg/bag or 25kg/drum
Delivery Time:	5-7 work days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	50kg per year

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Detailed Product Description

CAS No:	11041-12-6	Molecular Formula:	C27H47N
Molecular Weight:	385.66878	EINECS No:	234-270-8
PH:	4.0 To 6.0	Storage Condition:	Airtight Against Light, Dry And Ventilated.
Index Of Refraction:	1.62	Density:	1.24 G/cm3
Melting Point:	125 °C	Water Solubility:	Soluble
Flash:	204ºC	Boiling Point:	413.7 C At 760 MmHg
Appearance:	Light White To Light Yellow Crystal Or Crystalline Powder	USES:	Cholesterol-lowering Drugs, Used In Ⅱ Type Hyperlipidemia, Atherosclerosis And Other Diseases.
High Light:	pharma raw material , raw materials for medicines

Cholestyramine 11041-12-6 pharmaceutical raw material white powder has a slight odor

Basic parameter:

1. Product name :CHOLESTYRAMINERESIN

2. Product alias :cholestyraminechloride; Colestyramin; Cuemid; Polystyrenebenzyltrimethylaminoniumchloride; Quantalan; DOWEX1X2CL - FORM; CHOLESTYRAMINE. CHOLESTYRAMINERESIN

3. CAS no. : 11041-12-6

4. Molecular formula: C27H47N

5. Molecular weight: 385.66878

6. EINECS no. : 234-270-8

7. PH: 4.0 to 6.0

8. Storage condition: airtight against light, dry and ventilated.

9. Index of refraction: 1.62

10. Density: 1.24 g/cm3

11. Melting point: 125 °C

12. Water solubility: soluble

13. Flash: 204 DHS C

14. Boiling point :413.7 C at 760 mmHg

15. USES: cholesterol-lowering drugs, used in Ⅱ type hyperlipidemia, atherosclerosis and other diseases.

16. Appearance: light white to light yellow crystal or crystalline powder

Certificate of Analysis:

Product Name		Cholestyramine	Batch No.		191021
Packing		25kg/drum	Expiry Date		Oct.20,2022
Inspection Sheet No.		20191021	Exp.Date		Three Years
Report Date		Oct.21.2019
Standard	Enterprise standard
Items	Specification			Results
[Characteristics] [Identification] [Test] Acidity Dialysis quaternary Ammonium Chloride Loss on drying Residue on ignition Heavy metals Exchange capacity	White or off-white powder,odorless or some amine smell;Moisture absorption IR absorption spectrogram comply with refercnce standard spectrogram PH4.0-6.0 Complies 13.0-17.0%(On drying basis) 12.0%max 0.1%max Complies exchange sodium taurocholate per gram should be 2.0-2.4g on drying basis			off-white powder, some amine smell;Moisture absorption Complies 4.2 Complies 16.1% 7.2% Complies Complies 2.2g
Conclusion:Enterprise standard

Product overview:

Cholestyramine is one of the most important class of resin drugs that have a lipid-lowering effect. The effect of the drug on lowering cholesterol and the morbidity and mortality of coronary heart disease has been confirmed by long-term and large-scale clinical practice. However, because it has certain side effects and its lipid-lowering effect is not as good as that of "statins", it has been rarely used in clinical practice in recent years. However, when used in combination with other lipid-lowering drugs, it can improve the efficacy and reduce the side effects, which has good clinical significance.

Indications:

Mainly used in the treatment of Ⅱ type a high lipoprotein hematic disease, especially in the familial hypercholesterolemia. In addition, it is also used for the treatment of primary biliary cirrhosis, pruritus of drug-induced cholestasis jaundice, hypercholesterolemia, chronic cholecystitis, gallstones, porphyria, etc. Treatment of atherosclerosis: 4~ 5g, 3 times /d. Antipruritic: the initial dosage is 6 ~ 10g/d, and the maintenance dosage is 3g/d, taken in 3 times. Long-term use can reduce the intestinal combined with bile salt, resulting in poor fat absorption. Long-term use should be appropriately supplemented with vitamin A, D, K and other fat-soluble vitamins and calcium. People with gastrointestinal reactions can appropriately add stomach strengthening drugs.

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