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Clobetasol propionate 25122-46-7 skin care raw materials used to treat eczema

Clobetasol propionate 25122-46-7 skin care raw materials used to treat eczema

Clobetasol propionate 25122-46-7 skin care raw materials used to treat eczema
Clobetasol propionate 25122-46-7 skin care raw materials used to treat eczema

Large Image :  Clobetasol propionate 25122-46-7 skin care raw materials used to treat eczema Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: 25122-46-7

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 500kg per year
Detailed Product Description
CAS No: 25122-46-7 Molecular Formula: C25H32ClFO5
Molecular Weight: 466.97 EINECS No: 246-634-3
Melting Point: 195.5-197 ℃ Specific Rotation: +98 - +104°C
Boiling Point: 569.0±50.0°C Density: 1.1653
Storage Conditions: - 20 ° CFreezer Content: 99%
Standard Level: USP32 Appearance: White Crystalline Powder
High Light:

personal care raw materials

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skin treatment chemicals

Clobetasol propionate 25122-46-7 skin care raw materials used to treat eczema

 

Basic parameter:

1. Product name :Clobetasolpropionate
2. Product alias: propanoicacid [(9 r, r) 17-17 - (2 - chloro - 1 - oxoethyl) - 9 - fluoro - 11 - hydroxy - 10,13,16 - trimethyl - 3 - oxo - 6,7,8,11,12,14,15,16 - octahydrocyclopenta [a] phenanthren - 17 - yl] ester; Clobesol; Pregna - 1, 4 - diene - 3, 20 - dione, 21 - chloro - 9 - fluoro - 11 - beta, 17 - dihydroxy - 16 - beta - me; CLOBESTASOLPROPIONATE; CLOBETASOL 17 - PROPIONATE; CLOBETASOLEPROPIONATE; CLOBETASOLPROPIONATE; 21 - chloro - 9 - fluoro - 11 beta, 17 - dihydroxy - 16 beta - methylpregna - 1, 4 - diene - 3, 20 - dione17 - propionate
3. CAS no. : 25122-46-7
4. Molecular formula: C25H32ClFO5
5. Molecular weight: 466.97
6. EINECS no. : 246-634-3
7. Melting point: 195.5-197 ℃
8. Specific rotation :D+103.8°(c=1.04indioxane)
9. Boiling point: 569.0 + / - 50.0 ° C
10. Density: 1.1653
11. Storage conditions: - 20 ° CFreezer
12. Content: 99%
13. Standard level: USP38
14. Specific rotation: +98 - +104°C
15. Appearance: white crystalline powder
 
Certificate of Analysis:
Product name Clobetasol propionate
Batch No. 200302 Quantity 100.0kg
Mfg. Date Mar.,21, 2020 Expiry date Mar.,20, 2023
Specification USP38
Items Standard Results
Description White or almost white crystalline powder almost white crystalline powder
Solubility Practically insoluble in water,slightly soluble in benzene and diethyl ether ,sparingly soluble ethanol, soluble in acetone and in dimethyl sulfoxide, in chloroform, in methanol and in dioxane Complies
Identification (IR) Complies with the Standard Complies
Specific Rotation +98°~+104° +101.9°
Melting point about 196℃ 193.5~194.5℃
Loss on drying Max.2.0% 0.07%
Residue on ignition max. 0.1% 0.04%
Heavy Metals max.20ppm Complies

Related Substances

(HPLC)

-Single impurity N.m.t 1.0% 0.12%
-Sum impurity N.m.t 2.5% 0.18%
Organic volatile impurities
THF Not more than 720ppm Complies
Methanol Not more than 3000ppm Complies
DMF Not more than 880ppm Complies
Pyridine Not more than 200ppm Complies
Dichloromethane Not more than 600ppm Complies
Ethanol Not more than 5000ppm Complies
Acetone Not more than 5000ppm Complies
Assay(HPLC,basis on drying) 97.0%~102.0% 99.4%
Packaging and storage: Preserve in tight, light-resistant containers.
Conclusion: The test product complies with the requirements of USP38.

 

Structure:

Clobetasol propionate 25122-46-7 skin care raw materials used to treat eczema 0

 

 

Product overview:
Clobetasol propionate is a dermatological drug. External use is suitable for chronic eczema, neurodermatitis, psoriasis, palmoplantar pustules, lichen planus, lupus erythematosus and other effective external use of glucocorticoid treatment of pruritus and non-infectious inflammatory skin diseases.
 
Application:
clobetasol propionate is a synthetic and highly effective topical glucocorticoid. It has strong anti-inflammatory, anti-pruritic and capillary constriction effects, and its anti-inflammatory effect is about 112.5 times that of hydrocortisone, 2.3 times that of tamethasone sodium phosphate, and 18.7 times that of fluorosone. At the same time, it has the function of inhibiting cell mitosis and can effectively penetrate into the cuticle of skin.
 
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WuHan Dong Kang Yuan technology co., LTD

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Tel: 86-15377658509

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