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Depofemin 313-06-4 Female Hormones Estrogen White Powder For Women'S Health

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Depofemin 313-06-4 Female Hormones Estrogen White Powder For Women'S Health

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Product Details:

Place of Origin:	China
Brand Name:	DKY
Model Number:	313-06-4

Payment & Shipping Terms:

Minimum Order Quantity:	10g
Packaging Details:	1kg/bag or 25kg/drum
Delivery Time:	5-7 work days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	1000kg per year

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Detailed Product Description

CAS Number:	313-06-4	Molecular Formula:	C26H36O3
Molecular Weight:	396.56	EINECS No:	206-237-8
Melting Point:	151-152 °	Specific Rotation:	D25+45°
Boiling Point:	460.24 ° C	Density:	1.0828
Refractive Index:	1.4700	Steam Pressure:	5.73E-12mmHg At 25°C
Appearance:	White Powder	Packaging:	1KG/ Aluminum Foil Bag Detachable
High Light:	female hormones estrogen , women hormones estrogen

Depofemin 313-06-4 estrogen hormone raw material for women's health

Basic parameter:

1. Product name :Depofemin

2. Product names: 3 - cyclopentylpropanoicacid [(13 s) - 3 - hydroxy - 13 - methyl - 6,7,8,9,11,12,14,15,16,17 - decahydrocyclopenta [a] phenanthren - 17 - yl] ester; 3, 5 (10) -- triene - 3 in 2 - diol (17 - beta) - estra - 17 - cyclopentanepropanoate; 3, 5 (10) -- triene - 3 in 2 - diol (beta) of 17 - estra - 17 - cyclopentanepropanoate; 3 -,3,5 Hydroxyestra - 1 (10) -- trien - 17 - yl3 - cyclopentylpropanoate; B - estradiol17 - cypionate; Cyclopentanepropionicacid, 17 - esterwithestradiol; Cyclopentanepropionicacid, 3 -,3,5 hydroxyestra - 1 (10) -- trien - 17 beta ylester; Dep - Estro

3. The CAS number: 313-06-4

4. Molecular formula: C26H36O3

5. Molecular weight: 396.56

6. EINECS no. : 206-237-8

7. Melting point: 151-152 °

8. Specific rotation: D25+45°

9. Boiling point: 460.24 ° C

10. Density: 1.0828

11. Refractive index: 1.4700

12. Steam pressure: 5.73E-12mmHg at 25°C

13. Appearance: white powder

14. Packaging: 1KG/ aluminum foil bag detachable

Certificate of Analysis:

Product Name	Estradiol cypionate	Batch Size	30KG
Manufacturing Date	2020.01.03	Batch No.	20200103
Expiry Date	2022.01.02	Report Date	2020.01.10
Reference Standard	USP 36	Packing	Drum

TEST	ACCEPTANCE CRITERIONS	RESULTS
Identification	TLC	Positive
	UV spectrum	Positive
	IR spectrum	Positive
Appearance	White or Practically white crystalline powder	Confirm
Melting point	149 ~ 153℃	150~ 153℃
Specific roation	﹢39°~﹢44°	﹢41.5°
Loss on drying	≤1.0%	0.21%
Residue on ignition	≤0.2%	0.08%
Free acid	≤0.5%	0.29%
Assay	97.0 ~ 103.0％	98.68%

Depofemin 313-06-4 Female Hormones Estrogen White Powder For Women'S Health 0

Pharmacological effects:

The pharmacological action of estradiol cyclopropionate is basically the same as that of estradiol. Estradiol can by reducing the hypothalamus gonadotropin-releasing hormone (gonadotropin - releasinghormone, GnRH) release, leading to follicle stimulating hormone (folliedestimulatinghormone, FSH), luteinizing hormone (lureinizinghormone, LH) generated and secretion of luteinizing hormone (luecotropichorm - one) from the release of the pituitary gland is reduced, thereby inhibit ovulation. In men, the decrease of LH secretion can reduce the testicular testosterone secretion.

Matters needing attention:

The effects of estradiol cyclopropionate, ethinyl estradiol and diethylstilbestrol were similar except that the effect of ethinyl estradiol was about 20 times stronger than that of diethylstilbestrol.

1. Effects on the reproductive system. Estradiol cyclopropionate promotes secondary sexual characteristics and maturation of sexual organs in late adult women. In addition to maintaining secondary sexual characteristics for adult women, it can cause a series of changes in the endometrium under the feedback regulation of the hypothalamic-pituitary system, resulting in periodic menstruation. It also enhances uterine activity and improves the sensitivity of uterine smooth muscle to oxytocin. Promote vaginal epithelial hyperplasia and keratinization of surface cells. Estradiol cyclopropionate can also promote or inhibit the release of gonadotropin through its feedback effect on adenohypophysis and hypothalamus, indirectly affecting the morphology and function of ovaries.

2. On the mammary gland. Can stimulate the growth and development of mammary duct and acinar. The secretion of prolactin can be increased by stimulating the synthesis and release of prolactin by adenohypophysis or by inhibiting the secretion of prolactin by hypothalamus. Large doses inhibit lactation and may interfere with the action of prolactin at the breast level.

3. Effects on metabolism. It can activate the renin-angiotensin system in plasma, enhance the activity of osteoblasts, increase calcium salt deposition in bones, reduce glucose tolerance and blood cholesterol.

4. Effects on the coagulation process. Ring isoamyl propionate estradiol can be applied to a variety of clotting factors, such as make the clotting factors, Ⅱ, Ⅶ, Ⅸ and increased Ⅹ of antithrombin activity of Ⅲ has inhibitory effect.

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