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Dexamethasone 50-02-2 skin care raw materials sealed aluminum cans of white powder

Dexamethasone 50-02-2 skin care raw materials sealed aluminum cans of white powder

Dexamethasone 50-02-2 skin care raw materials sealed aluminum cans of white powder
Dexamethasone 50-02-2 skin care raw materials sealed aluminum cans of white powder

Large Image :  Dexamethasone 50-02-2 skin care raw materials sealed aluminum cans of white powder Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: 50-02-2

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Packaging Details: 10g/bag or 1kg/bottle
Delivery Time: 5-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 1000kg per year
Detailed Product Description
Molecular Formula: C22H29FO5 Molecular Weight: 392.46100
CAS Number: 50-02-2 EINECS No: 200-003-9
Appearance: White Powder Melting Point: 255 ~ 264 ℃
Specific Rotation: 75(º,C=1, DIOXANE) Solubility: Soluble In Water, 10mg/100mL, 25℃; Ethanol, 1mg/mL.
Density: 1.32g /cm3 Boiling Point: 568.2ºC At 760 MmHg
Flash: 297.5ºC Index Of Refraction: 1.591
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Dexamethasone 50-02-2 skin care raw materials sealed aluminum cans of white powder

 

Basic parameter:

1. Product name: dexamethasone
2. Product alias: Dexamethasone; Auxiron; Pregna - 1, 4 - diene - 3, 20 - dione,,17,21 - trihydroxy 9 - fluoro - 11-16 - methyl -, 16 (11 beta, alpha) -; Mk125; 9 a 16 - fluoro - a - methylprednisolone
3. Molecular formula: C22H29FO5
4. Molecular weight: 392.46100
5. CAS number: 50-02-2
6. EINECS no. : 200-003-9
7. Appearance: white powder
8. Melting point: 255 ~ 264 ℃
9. Specific rotation: 75 (,C=1, DIOXANE)
10. Solubility: soluble in water, 10mg/100mL, 25℃; Ethanol, 1mg/mL.
11. Density: 1.32g /cm3
12. Boiling point: 568.2℃ at 760 mmHg
13. Flash: DHS 297.5℃
14. Index of refraction: 1.591
 
Certificate of Analysis:
Product Name Dexamethasone Base Cas No 50-02-2
Batch No 20190803 MFG Date Aug.03.2019
Report Date Aug.03.2019 Expiry Date Jul.31. 2021
Quantity 100Kgs Confirm EP7.0
Item Specification Result
Appearance White or almost White,
crystalline powder
Almost White
crystalline powder
Identification B:IR
C:TLC
Conforms
Specific optical
rotation
+75°~+80° +76.4°
Result
substances
Individual impurity≤0.5% 0.37%
Total impurities≤1.0% 0.85%
Loss on drying ≤0.5% 0.20%
Assay 97.0%-103.0% 99.8%

Conclusion:

The above product conforms to the specification of EP7.0

 

Structure:

Dexamethasone 50-02-2 skin care raw materials sealed aluminum cans of white powder 0

 

 

Pharmacological effects:
Dexamethasone (dexamethasone) is a glucocorticoid. Its derivative has the hydrogenation kedipine, prednisone and so on, its pharmacology function mainly is the anti - inflammation, anti - poison, anti - allergy, anti - rheumatism, the clinical use is widespread. It was easily absorbed from the digestive tract, and its plasma t1/2 was 190 minutes, tissue t1/2 was 3 days, and the peak blood concentration of dexamethasone sodium phosphate or dexamethasone acetate was reached at l hours and 8 hours respectively after intramuscular injection. The plasma protein binding rate of the drug was lower than that of other corticosteroid drugs. The anti-inflammatory activity of 0.75mg of the drug was equivalent to 5mg of prednisolone. Adrenocortical hormone drugs, anti-inflammatory, anti - allergic and anti - toxic than prednisone, water and sodium retention and promote potassium release is very light, can be intramuscular injection or static drop on the pituitary - adrenal inhibition of a strong.
1. Anti-inflammatory effect: it can reduce and prevent the tissue's response to inflammation, thus reducing the expression of inflammation. Hormones inhibit the aggregation of inflammatory cells, including macrophages and leukocytes, at the site of inflammation, and inhibit phagocytosis, release of lysosomal enzymes, and synthesis and release of inflammatory chemical mediators.
2. The immunosuppressive effect: including prevent or inhibit cell-mediated immune response, delayed allergic reaction, reduce T lymphocytes, monocytes, and the number of eosinophilic cells, reduce the immunoglobulin with cell surface receptor binding ability, and inhibit the synthesis and release of interleukin, thereby reducing T lymph cell to cell transformation, and reduce the expansion of the primary immune response. It can reduce the immune complex through the basement membrane and reduce the complement component and the concentration of immunoglobulin.

 

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