WuHan Dong Kang Yuan Technology co., LTD

 

Integrity-based service-oriented Kangyuan products must be boutiques.

Home
Products
About Us
Factory Tour
Quality Control
Contact Us
Request A Quote
Home ProductsPharmaceutical Intermediates

Dexmedetomidine HCl 145108-58-3 Pharmaceutical Raw Material USP/EP 1kg/bag

Dexmedetomidine HCl 145108-58-3 Pharmaceutical Raw Material USP/EP 1kg/bag

Dexmedetomidine HCl 145108-58-3 Pharmaceutical Raw Material USP/EP 1kg/bag
Dexmedetomidine HCl 145108-58-3 Pharmaceutical Raw Material USP/EP 1kg/bag

Large Image :  Dexmedetomidine HCl 145108-58-3 Pharmaceutical Raw Material USP/EP 1kg/bag Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: 145108-58-3

Payment & Shipping Terms:

Minimum Order Quantity: 100g
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 1000kg per year
Detailed Product Description
CAS No: 145108-58-3 Molecular Formula: C13H17ClN2
Molecular Weight: 236.74048 EINECS No: 682-047-2
Melting Point: 156.5 To 157.5 ° Specific Rotation: +52.4° (c = 1 In Water)
Density: 1.17g /cm3 Boiling Point: 381.9 C At 760 MmHg
Flash: 191.3 ° C Vapor Pressure: 1.08E-05mmHg At 25°C
Storage Conditions: Desiccate At RT Solubility: H2O: Soluble20mg/mL, Clear
Optical Activity: [α]/D +48 To +58°, C = 1 In H2O Appearance: White Or White-like Crystalline Powder
High Light:

pharma raw material

,

raw materials for medicines

Dexmedetomidine HCl 145108-58-3 Pharmaceutical Raw Material USP/EP 1kg/bag
 
Basic parameter:
1. Product name: Dexmedetomidinehydrochloride
2. Product nicknames :4-[(1r)-1-(2,3-dimethylphenyl)ethyl] -3h-imidazoleo; 4 - ((s) - alpha, 2, 3 - trimethylbenzyl) imidazolemonohydrochloride; DEXMEDETOMIDINEHCL; DEXMEDETOMIDINEHYDROCHLORIDE; DEMEDETOMIDINEHCL; Dexmedetomidine (Pilot); ((addition)) - Medetomidinehydrochloride; 4 - ((S) - alpha, 2, 3 - Trimethylbenzyl) imidazolemonohydrochloride
3. CAS no. : 145108-58-3
4. Molecular formula: C13H17ClN2
5. Molecular weight: 236.74048
6. EINECS no. : 682-047-2
7. Melting point: 156.5 to 157.5 °
8. Specific rotation: +52.4° (c = 1 in water)
9. Density: 1.17g /cm3
10. Boiling point: 381.9 C at 760 mmHg
11. Flash: 191.3 ° C
12. Vapor pressure: 1.08E-05mmHg at 25°C
13. Storage conditions: Desiccate at RT
14. Solubility: H2O: soluble20mg/mL, clear
15. Optical activity: [α]/D +48 to +58°, c = 1 in H2O
16. Appearance: white or white-like crystalline powder
 
Pharmacological effects:
Dexmedetomidine is a relatively selective a2-adrenergic receptor agonist with a sedative effect. The selective effect of dexmedetomidine on a2-adrenergic receptors was observed in animals with slow intravenous infusion of dexmedetomidine from 10 to 300ug/kg, but at higher doses (³ Both a1 and a2- receptors were affected by slow intravenous infusion or rapid intravenous infusion.
 
Product details:
Dexmedetomidine is an active dextro isomer of medetomidine, which has anti-sympathetic, sedative and analgesic effects. Compared with medetomidine, this product is more selective to the central lumetomidine 2-epinephrine receptor, which is 8 times higher than clonidine.
In mediating the main pharmacological and therapeutic effects of this product, the leugh2a receptor subtype plays an important role. Leugh2a receptor exists in the presynaptic and postsynaptic regions and is mainly involved in inhibiting the release of norepinephrine and neuronal excitation. This product inhibits the release of norepinephrine and stops the transmission of pain signals by stimulating the presynaptic membrane leuben2 receptor. By activating the postsynaptic membrane receptor, dexmedetomidine inhibited sympathetic nerve activity, resulting in decreased blood pressure and heart rate. Binding to the lebenium lebenium 2 receptor in the spinal cord to produce analgesic effect can result in sedation and relief of anxiety. This product can also reduce the dose of anesthetics, improve the stability of hemodynamics and reduce the incidence of myocardial ischemia during surgery.
 
I am Angela
Contact Angela, you would never regret.
email: zs@dkybpc.com
Tel: +86-15377658509, you can add me on WeChat or Skype or Whatsapp if you are using that.
 

Contact Details
WuHan Dong Kang Yuan technology co., LTD

Contact Person: Angela

Tel: 86-15377658509

Send your inquiry directly to us