Donepezil HCl Active Pharmaceutical Ingredients 120011-70-3 For Alzheimer'S Disease

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Name: Donepezil HCl Active Pharmaceutical Ingredients 120011-70-3 For Alzheimer'S Disease
Brand: DKY
SKU: 120011-70-3

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Detailed Product Description

CAS No:	120011-70-3	Molecular Formula:	C24H30ClNO3
Molecular Weight:	415.95	EINECS No:	620-543-2
Melting Point:	220-222 ° C	Boiling Point:	527.9 C At 760 MmHg
Flash:	273.1ºC	Steam Pressure:	3.11e-11mmhg At 25°C
Storage Conditions:	- 20 ° C Freezer	Appearance:	White To Off-white Crystalline Solid
High Light:	active pharma ingredients , api pharmaceuticals

Donepezil HCl 120011-70-3 Active Pharmaceutical Ingredients for alzheimer's disease

Basic parameter:

1. Product name: donepezilch

2. Product nicknames: donepezile; Bnag; E2020 (pharmaceutical); AKOS226-31; ARICEPT; DONEPEZILHCL; DONEPEZILHYDROCHLORIDE; E - 2020.

3. CAS no. : 120011-70-3

4. Molecular formula: C24H30ClNO3

5. Molecular weight: 415.95

6. EINECS no. : 620-543-2

7. Melting point: 220-222 ° C

8. Boiling point :527.9 C at 760 mmHg

9. Flash: DHS 273.1 C

10. Steam pressure: 3.11e-11mmhg at 25°C

11. Storage conditions: - 20 ° C Freezer

12. Appearance: white to off-white crystalline solid

Certificate of Analysis:

TEST ITEM	SPECIFICATION	RESULT
Appearance	Off white to white crystalline powder	Complies
Solubility	Freely soluble in chloroform, soluble in water and Acetic acid, slightly soluble in Acetonitrile and ethanol, insoluble in Ethylacetoacetate and n-hexane.	Complies
Identification	(1)By IR absorption ,To match with working standard.	Complies
	(2) The retention time of the major peak of the sample should accord with that of the working standard.	Complies
	(3) Test for chlorides. Reponds to the test for Chlorides.	Complies
Water	≤0.4%	0.31%
Residue on ignition	≤0.1%	0.02%
Related substance	Desbenzyl donepezl^a≤0.15% Donepezil pyridine analog^b≤0.15% Donepezilzilbenzyl bromide^c≤0.15% Dehydrodeoxy donepezil^d≤0.15% Deoxy donepezil^e≤0.15% Any Unkonwn single impurity≤0.10% Total ≤0.5%	Not detected Not detected 0.02% Not detected Not detected 0.05% 0.18%
Heavy metal	≤20ppm	≤20ppm
Residual Solvents	Methanol≤0.3% Ethanol≤0.5% Ethyl acetate≤0.5% Toluene≤0.089% Acetic acid≤0.5%	Not detected Not detected Not detected Not detected Not detected
Assay	On dried base, C₂₄H₂₉NO₃·HCl should be 98.0% to 102.0%.	99.52%