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Ibuprofen 15687-27-1 Medicine Raw Materials Chemicals For Drugs Company

Ibuprofen 15687-27-1 Medicine Raw Materials Chemicals For Drugs Company

Ibuprofen 15687-27-1 Medicine Raw Materials Chemicals For Drugs Company
Ibuprofen 15687-27-1 Medicine Raw Materials Chemicals For Drugs Company

Large Image :  Ibuprofen 15687-27-1 Medicine Raw Materials Chemicals For Drugs Company Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Price: $70-100/kg
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-8 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 300 ton per year
Detailed Product Description
CAS No: 15687-27-1 Molecular Formula: C13H18O2
Molecular Weight: 206.28 EINECS No: 239-784-6
Melting Point: 77-78 ° C Specific Rotation: [α]D20-1~+1°(c=1,C2H5OH)
Boiling Point: 157 ° C Density: 1.0364
Refractive Index: 1.5500 Flash: 9 ℃
Storage Conditions: - 20 ℃ Freezer Solubility: Practicallyinsolubleinwater Freelysolubleinacetone, Inmethanolandinmethylenechloride Itdissolvesindilutesolutionsofalkalihydroxidesandcarbonates.
High Light:

raw materials for drugs

,

pharmaceutical industry raw materials

Ibuprofen API, 15687-27-1, Drug Factory, Pharmaceutical Chemical, Drugs Company

 

Basic parameter:

1. Product name :Ibuprofen
2. Product nicknames :alpha-(4-isobutylphenyl)propionicacid; Alpha - (p - isobutylphenyl) propionicacid; Alpha - 2 - (p - Isobutylphenyl) propionicacid; Alpha - methyl - 4 - (2 - methylpropyl) - benzeneaceticaci; Alpha - p - isobutylphenylpropionicacid; Andran; Anflagen; Artril300
3. CAS no. : 15687-27-1
4. Molecular formula: C13H18O2
5. Molecular weight: 206.28
6. EINECS no. : 239-784-6
7. Melting point: 77-78 ° C (lit.)
8. Specific rotation: [lucume] d20-1 ~ +1°(c=1,C2H5OH)
9. Boiling point: 157 ° C (4 MMHG)
10.Density: 1.0364 (roughestimate)
11. refractive index: 1.5500 (estimate)
12. Flash: 9 ℃
13. Storage conditions: - 20 ℃ Freezer
14. Solubility: Practicallyinsolubleinwater freelysolubleinacetone, inmethanolandinmethylenechloride Itdissolvesindilutesolutionsofalkalihydroxidesandcarbonates.

 

Certificate of Analysis:

Product Name Ibuprofen(75Grade) Batch No. 20190719
MFG. Date 2019.07.20 Testing Date 2019.07.19
Retest Date 2021.07.19 Standard USP28
ITEMS SPECIFICATIONS RESULTS
Characteristics White crystalline powder Conforms
Solubility Practically insoluble in water ;very soluble in alcohol , in methanol ,in acetone, and in chloroform; slightly soluble in ethyl acetate Conforms

Identification

AIR

 

B.UV

 

C.HPLC

a. Sample IR spectrum corresponds to that of the standard Conforms
  B. Sample UV spectrum does not differ from that of the standard by more than 3.0% Conforms
  C. Retention time corresponds to that of the standard Conforms
Water Content not more than1.0% 0.12%
Heavy Metals not more than0.002% <0.002%
Residual on Ignition not more than0.5% 0.02%
Chromatographic Purity 2-[3-(2-methylpropyl)phenyl]propanic acid :not more than0.15% 0.03%
  2-[4-methyl phenyl]propanic acid :not more than0.15% 0.0%
  2-[4-ethyl phenyl]propanic acid :not more than0.15% 0.01%
  2-[4-propylphenyl]propanic acid :not more than0.15% 0.01%
  2-[4-butylphenyl]propanic acid :not more than0.1% 0.0%
  Any unknown impurities not more than 0.05% 0.02%
  Total impurities :not more than 0.6% 0.07%
4-Isobutylacetophenone Not more than 0.1% 0.0%
Assay(dried basis) 97.0%-103.0% 100.1%
ADDITIONAL TESTS

Residual solvents

(Petroleum ether)

Not more than 250ppm 79ppm
Bulk Density 0.25-0.50g/ml 0.43g/ml
Tapped density 0.50-0.75g/ml 0.64g/ml
Median particle size 60-90um 89.84um
Conclusion The product meets USP28 specifications

 

Structure:

Ibuprofen 15687-27-1 Medicine Raw Materials Chemicals For Drugs Company 0

 

USES:
1. It has anti-inflammatory, analgesic and antipyretic effects. Treatment of rheumatism and rheumatoid arthritis is less effective than acetylsalicylic acid and butazone. Suitable for the treatment of rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, ankylosis and neuritis. It was the thirteenth most expensive drug sold in the United States in 1985.
2. Used as PG synthase inhibitor, it has the functions of antipyretic, analgesic and anti-inflammatory
3. The inhibitory activity of cyclooxygenase (COX) inhibitor on cox-1 was greater than that on cox-2.
 
 
Indications:
1, relieve rheumatoid arthritis, osteoarthritis, spondylopathy, gout arthritis, rheumatoid arthritis and other chronic arthritis of the acute onset or persistent joint swelling and pain symptoms, no etiological treatment and control of the course of disease.
2, the treatment of non-articular soft tissue rheumatic pain, such as shoulder pain, tenosynovitis, bursitis, myalgia and post-exercise injury pain.
3. Acute mild to moderate pain, such as: after surgery, after trauma, after strain, primary dysmenorrhea, toothache, headache, etc.
4, has the antipyretic effect to the adult and the child's fever.
 
 

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WuHan Dong Kang Yuan technology co., LTD

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Tel: 86-15377658509

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