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Indometacin 53-86-1 pharmaceutical raw material used to reduce inflammation and relieve pain

Indometacin 53-86-1 pharmaceutical raw material used to reduce inflammation and relieve pain

Indometacin 53-86-1 pharmaceutical raw material used to reduce inflammation and relieve pain
Indometacin 53-86-1 pharmaceutical raw material used to reduce inflammation and relieve pain

Large Image :  Indometacin 53-86-1 pharmaceutical raw material used to reduce inflammation and relieve pain Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: 53-86-1

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 50 tons per year
Detailed Product Description
CAS Number: 53-86-1 EINECS No: 200-186-5
Molecular Formula: C19H16ClNO4 Molecular Weight: 357.79
Melting Point: 155-162 ℃ Boiling Point: 499.4°C At 760 MmHg
Flash: 255.8 ° C Vapor Pressure: 8.61E-11mmHg At 25°C
Properties: White Or Yellowish Crystalline Powder. Almost Tasteless And Odorless. Solubility: Soluble In Acetone, Slightly Soluble In Ethanol, Ether, Chloroform And Methanol, Slightly Soluble In Benzene, Very Slightly Soluble In Toluene, Almost Insoluble In Water. Soluble In Sodium Hydroxide Solution.
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Indometacin 53-86-1 pharmaceutical raw material used to reduce inflammation and relieve pain

 

Basic parameter:

1. Product name: Indomethacin
2. Product alias: Indomethacin methanol solution; Indomethacin crystalline; Indomethacin usp. Indometacin. 1 - (4 - chlorobenzoyl) - 5-2 - methylindol - 3 - methoxy - ylacetic acid; {1 - [(4 chlorophenyl) carbonyl] - 5 - methoxy - 2 - methyl - 1 h - indol - 3 - yl} acetate
3. CAS number: 53-86-1
4. EINECS no. : 200-186-5
5. Molecular formula: C19H16ClNO4
6. Molecular weight: 357.79
7. Melting point: 155-162 ℃
8. Boiling point: 499.4°C at 760 mmHg
9. Flash: 255.8 ° C
10. Vapor pressure: 8.61E-11mmHg at 25°C
11. Properties: white or yellowish crystalline powder. Almost tasteless and odorless.
12. Solubility: soluble in acetone, slightly soluble in ethanol, ether, chloroform and methanol, slightly soluble in benzene, very slightly soluble in toluene, almost insoluble in water. Soluble in sodium hydroxide solution.
 
Certificate of Analysis:
Product Name Indomethacin Batch No. 200527
MFG. Date 2020.05.27 Exp Date 2022.05.26
Quantity 500.40kg According to BP2010
ITEMS SPECIFICATIONS RESULTS
Characteristics White or yellow crystalline powder Yellow crystalline powder
Identification    
A:Melting point 158℃~162℃ 160.0℃~162.0℃
C:Infrared Absorpt on spectrum Meets the requirements Meets the requirements
Tests    
Related substances Meets the requirements Meets the requirements
Heavy metals ≤20ppm <20ppm
Loss on drying ≤0.5% 0.05%
Sulphated ash ≤0.1% 0.05%
Assay 98.5%~100.5% 99.59%
Particle Size 80%particle less than 80um Meets the requirements
Conclusion The above product conforms to BP2010

 

Structure:

Indometacin 53-86-1 pharmaceutical raw material used to reduce inflammation and relieve pain 0

 

 

USES:
1. This product has obvious anti-inflammatory and antipyretic effect, and is mainly used for rheumatic arthritis, ankylosing photospondylitis, osteoarthritis and so on, in which salicylic acid drugs are not easy to be tolerated or have no significant curative effect.
2. Non-hormonal anti-inflammatory and analgesic
3. Cyclooxygenase (COX) inhibitor, selectively inhibiting cox-1; Blocking the biosynthesis of prostatic cord. In medicine, anti-inflammatory, antipyretic effect is obvious, mainly used for salicylic acid drugs are not easy to tolerate or efficacy is not significant rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and so on.
 
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