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Nicotinamide 98-92-0 Cosmetic Raw Materials crystalline powder For Skin Whitening
Product Details:
Payment & Shipping Terms:
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Detailed Product Description
| CAS No: | 98-92-0 | Molecular Formula: | C6H6N2O |
|---|---|---|---|
| Molecular Weight: | 122.12 | EINECS No: | 202-713-4 |
| Melting Point: | 128-131 °C(lit.) | Boiling Point: | 150-160 °C |
| Density: | 1.40 | Steam Density: | 4.22 (vs Air) |
| Refractive Index: | 1.4660 | Flash Point: | 182 °C |
| Storage Conditions: | 0-6°C | Appearance: | White Crystalline Powder; Odorless Or Nearly Odorless, With A Bitter Taste; |
| Spontaneous Combustion Point Or Ignition Temperature: | 480ºC | Solubility: | 1g Of This Product Is Soluble In 1ml Water, 1.5ml Alcohol And 10ml Glycerin, Insoluble In Ether. |
| High Light: | raw materials used in cosmetics,makeup raw materials |
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Nicotinamide 98-92-0 cosmetic raw materials for skin whitening
Basic parameter:
1. Product name :Nicotinamide
2. Product alias: 3-pyridinecarboxamide; 3 - PYRIDINECARBOXYLICACIDAMIDE; 3 - PYRIDINECARBOXYLICAMIDE; TIMTEC - BBSBB004283; NICETHAMIDUM; NIACINAMIDE. NICOTINICACIDAMIDE; NICOTINAMIDE
3. CAS no. : 98-92-0
4. Molecular formula: C6H6N2O
5. Molecular weight: 122.12
6. EINECS no. : 202-713-4
7. Melting point: 128-131 °C
8. Boiling point: 150-160 °C
9. Density: 1.40
10. Steam density: 4.22 (vs air)
11. Refractive index: 1.4660 (estimate)
12. Flash point: 182 °C
13. Storage conditions: 0-6°C
14. Appearance: white crystalline powder; Odorless or nearly odorless, with a bitter taste;
15. Spontaneous combustion point or ignition temperature: 480℃
16. Solubility: 1g of this product is soluble in 1ml water, 1.5ml alcohol and 10ml glycerin, insoluble in ether.
Certificate of Analysis:
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Product Name |
Nicotinamide |
Quantity |
2000kg |
|
Batch No |
2019.5.28 |
Packing |
25kg/bag |
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MFG. Date |
MAY.28,2019 |
Exp. Date |
May.27,2021 |
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Pef. standard |
USP28 |
|
Test Items |
Specification |
Test Results |
|
Appearance |
White Crystal |
Complies |
|
Identification |
Positive |
Complies |
|
Related substances |
Test as per USP |
Complies |
|
Assay |
98.5～101.5% |
99.8% |
|
Melting Point |
128～131℃ |
129.0～130.0℃ |
|
Loss on drying |
≤0.5% |
0.2% |
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Residue on ignition |
≤0.1% |
0.05% |
|
Heavy metals |
≤0.002% |
＜0.002% |
|
PH |
5.5～7.5 |
6.0 |
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Conclusion |
It meets the quality standard of USP28 |
Application in cosmetics:
1. Reduce and prevent the dark, yellow and vegetable color of skin in the early aging process.
2. Repair damaged cuticle lipid barrier and improve skin resistance. Topical nicotinamide reduces the production of fatty acids and triglycerides in sebum, thereby narrowing pores and reducing the severity of acne.
3. Deep water-locking effect on skin. Ceramide is an important component of skin barrier. The levels of ceramide in the cuticle of atopic dermatitis, aged skin and dry skin in winter were significantly reduced. Nicotinamide enhances skin barrier function by increasing the content of ceramide in cuticle and reducing the loss of percutaneous moisture.
A. principle of action
When the concentration of nicotinamide role of 0.25 and 1.25 mg/ml, the melanin cell of melanin body movement rate increased significantly (P < 0.05), at the same time, intensity of melanin in the cell body decline with the increase of concentration of nicotinamide. Conclusion: nicotinamide in melanin and can speed up the transfer process of melanocyte in melanin body movement rate, display nicotinamide cells of calcium pump, power Dynein protein expression and regulation effects of melanin body movement, mass action concentrations is one important factor adjustment.
As skin ages, the levels of NADH and NADPH decline, and both control the process of synthesis and breakdown in cells. As a precursor of NADH and NADPH, nicotinamide can play a role by regulating the level balance in the body of both NADH and NADPH. High levels of NADPH play a powerful antioxidant role, preventing spontaneous glycosylation of proteins and sugars. Glycosylated proteins are deposited in the dermis and appear yellowish brown. There are five times more saccharification products in the dermal collagen of skin aged 80 than in skin aged 20. Glycosylated proteins play an important role in the dark and yellow appearance of aging skin. Nicotinamide increases NADPH to play an anti-glycosylated role, thereby reducing yellowing of aging skin, reducing facial color and improving skin quality.
B. A true and effective test
With age, the skin becomes dark and dull, which can be improved by topical nicotinamide. A randomized study showed that using the niacinamide solution twice a day significantly improved skin texture and significantly reduced fine lines and wrinkles from week 8. At week 12, the skin became elastic, pigmentation and erythema were significantly reduced, and the dark and yellow color were significantly reduced.
Contact Details
WuHan Dong Kang Yuan technology co., LTD
Contact Person: Angela
Tel: 86-15377658509
Send your inquiry directly to us
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