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Pharmaceutical Raw Materials L-Histidine CAS No 71-00-1 API Intermediates

Pharmaceutical Raw Materials L-Histidine CAS No 71-00-1 API Intermediates

Pharmaceutical Raw Materials L-Histidine CAS No 71-00-1 API Intermediates
Pharmaceutical Raw Materials L-Histidine CAS No 71-00-1 API Intermediates

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Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: H1001

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Price: $80-100/kg
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 100 tons per year
Detailed Product Description
CAS No: 71-00-1 Melting Point: 282 ° C
Specific Rotation: 12.4 ° (C = 11,6nhcl) Boiling Point: 278.95 ° C
Density: 1.3092 Refractive Index: 13 ° (C = 11,6mol / Lhcl)
Storage Condition: Storeatrt Solubility: H2O: 50mg / Ml
High Light:

amino acid supplements

,

nutritional raw materials

pharmaceutical raw materials L-histidine 71-00-1 API Manufacturer made in China

 

Basic parameter:

1. Product Name: L-histidine

2. Other names: L-histidine, free base; L-His = h-his-oh; (s) - 2-amino-3 - (4-imidazolyl) propionic acid ~ h-his-oh; L-histidine base; h-his-oh; his

3. CAS No.: 71-00-1

4. Melting point: 282 ° C (Dec.) (lit.)

5. Specific rotation: 12.4 ° (C = 11,6nhcl)

6. Boiling point: 278.95 ° C (rough estimate)

7. Density: 1.3092

8. Refractive index: 13 ° (C = 11,6mol / lhcl)

9. Storage condition: storeatrt

10. Solubility: H2O: 50mg / ml

 

Certificate of Analysis:

Product Name:L-Histidine
Batch No:20190306 Quantity:1000KGs
Manufacture Date:03.06.2019 Expiry Date:03.05.2021
Items Specifications Results

Test Method

Appearance

White crystals or crystalline powder

Conforms Visual
Identification

Infrared Absorption

Conforms USP
Assay 98.5~101.5% 99.6% USP

Residue on ignition

≤0.4% 0.07% USP
Chloride(Cl) ≤0.05% <0.05% USP
Sulfate(SO4) ≤0.03% <0.03% USP
Iron(Fe) ≤30ppm <30ppm USP

Heavy metals(Pb)

≤15ppm <15ppm USP

 

Related compounds

Not more than 0.5% of any individual impurity is found;not more than 2.0% of total impurities is found.

 

Conforms USP

Specific rotation[a]D25

+12.6°~+14.0° +12.9° USP
PH 7.0~8.5 7.8 USP

Loss on drying

≤0.2% 0.11% USP

Conclusion:This batch is conforming with the standard of USP39.

 

Structure:

Pharmaceutical Raw Materials L-Histidine CAS No 71-00-1 API Intermediates 0

 

 

USES:
1. Nutritional supplements. Amino acid infusion and synthesis of essential components of amino acid preparation. Medicine used to treat gastric ulcer, anemia, allergies, etc.
2. It is used in biochemical research and medicine for the treatment of gastric ulcer, anemia and allergy.
3. Amino acids. Amino acid infusion and the main components of the synthesis of amino acid preparation, used for the treatment of gastric ulcer, anemia and angina pectoris, aortic inflammation, cardiac dysfunction and other cardiovascular system diseases. Adverse reactions and contraindications: low toxicity, adult dose of >64g/ day. If hydrochloric acid histamine acid injection has headache, flushing, heat.
4. As a nutrient fortifier, it is an important component of amino acid infusion and compound amino acid preparation. It can be used to treat gastric ulcer. It is also used in biochemical research. Used as pharmaceutical raw materials and food additives.

 

Preparation method:

It is extracted from pig blood and cow blood. Pig blood was dried with spray dried blood powder and 18kg blood powder per 100kg pig blood. L-histidine is often used as its hydrochloride ([7048-02-4]). The eluate containing L-histidine is concentrated to crystallize, adjusted to pH 2.5 with hydrochloric acid while it is hot, and ethanol twice the amount of solution is added immediately. After standing, settling and filtering, the crude L-histidine hydrochloride is obtained. After decolorization, recrystallization and drying, the finished product is obtained. L-histidine can also be extracted from the hydrolysates of defatted soybeans.

Purpose:

It is an important component of amino acid infusion and compound amino acid preparation. It can be used to treat gastric ulcer. It is also used in biochemical research.

 

 

 

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