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Pharmaceutical Raw Materials Meloxicam 71125-38-7 99% Assay Light Yellow Solid

Pharmaceutical Raw Materials Meloxicam 71125-38-7 99% Assay Light Yellow Solid

Pharmaceutical Raw Materials Meloxicam 71125-38-7 99% Assay Light Yellow Solid
Pharmaceutical Raw Materials Meloxicam 71125-38-7 99% Assay Light Yellow Solid

Large Image :  Pharmaceutical Raw Materials Meloxicam 71125-38-7 99% Assay Light Yellow Solid Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-8 work days
Supply Ability: $165-185/kg
Detailed Product Description
DeliveryTime: Prompt PackAge: 1kg Aluminum Foil Bag Or 25kg/drum,according To The Clients Requirement
Storage: Store In Dry, Dark And Ventilated Place LimitNum: 500 Gram Or 1 Kilogram
Transportation: Air Or Ocean Or Rail Or Parcel Post(EMS、TNT、DHL、UPS、FEDEX),or According Your Requirement Port: Any Port In China
Assay: 99% Shelf Life: Two Years
Origin: Hubei Transport Package: Discreet And Tight
Specification: 100% Qualified
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pharmaceutical raw materials Meloxicam 71125-38-7 API Manufacturer made in China

 

Basic parameter:
1. Product Name: Meloxicam
2. Synonyms: MOBIC;MOBEC;UH-AC 62XX;METACAM;MELOXICAM;4-HYDROXY-2-METHYL-N-(5-METHYL-2-THIAZOLYL)-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE;4-HYDROXY-2-METHYL-N-(5-METHYL-2-THIAZOYL)-2H-1,2-BENZOTHIAZINE-3-CARBOXAMIDE-1,1-DIOXIDE;Meiloxicam
3. CAS: 71125-38-7
4. MF: C14H13N3O4S2
5. MW: 351.4
6. Meloxicam Chemical Properties
7. Melting point 255 °C
8. storage temp. 0-6°C
9. Meloxicam Usage And Synthesis
10. Chemical Properties Light Yellow Solid
11. Usage Preferential cyclooxygenase (COX-2) inhibitor. Sudoxicam and Meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.
12. Usage angiotensin 2 receptor antagonist
13. Usage For symptomatic treatment of arthritis and osteoarthritis.
14. Usage Preferential cyclooxygenase (COX-2) inhibitor. Used as an anti-inflammatory.

 

Certificate of Analysis:

Product name:Meloxicam Date of Mfg:2020.04.10
Batch No:20200404 Report Date:2020.04.18
Batch Size:125kg Retest Date:2025.04.09
Quality Specification:EP8.5 Package:25kg/drum
Subject Specification Result
Appearance A pale yellow powder A pale yellow powder
Identification Should comply with the IR spectrum Comply with the IR spectrum
Related substances Impurity A ≤0.1% Not detected
  Impurity B ≤0.1% Not detected
  Impurity C ≤0.05% Not detected
  Impurity D ≤0.05% 0.03%
  Any other impurity ≤0.10% <0.03%(260nm)
  Total impurities ≤0.3% 0.06%
Heavy metals ≤20ppm <20 ppm
Loss on drying ≤0.5% 0.02%
Sulphated ash ≤0.1% 0.05%
Assay,on dried basis 99.0%~101.0% 99.8%
Residual solvents Ethanol ≤5000 ppm 184 ppm
  Xylene ≤2170 ppm Not detected
Conclusion:Up to standard.

 

Structure:

 

Pharmaceutical Raw Materials Meloxicam 71125-38-7 99% Assay Light Yellow Solid 0

 

Product details:

Meloxicam (meloxicam), chemical name 4-hydroxyl-2-methyl-n -(5-methyl-2-thiazolyl) -2h-1, 2-benzothiazine-3-carboxylamide 1, 1-oxide, is a non-steroidal anti-inflammatory drug. It was first listed in South Africa in 1996 by the German company BoehringerIngelheim. It has analgesic, anti-inflammatory and antipyretic effects, and is suitable for symptomatic treatment of rheumatoid arthritis and painful osteoarthritis. The mechanism of action of nsaids is to inhibit the synthesis of inflammatory prostaglandins (PGs) by inhibiting cyclocytes (COX). Cycdroxygenase (COX) is a membrane-bound serum protein and glycoprotein that catalyzes the oxidation of arachidonic acid (AA) to prostaglandin G2(PGG2), which is then reduced from PGG2 to PGH2. COX has two heterogeneous forms: cyclooxygenase-1 (cox-1) -structural enzyme and cyclooxygenase-2 (cox-2) -pgg2-induced enzyme. The inducible enzyme cox-2 is induced by inflammatory regulation and is involved in the regulation of inflammatory response. The structural enzyme cox-1 is necessary for normal physiological processes and exists in most tissues. Its function is to synthesize PG to regulate the normal physiological activities of cells, protect the gastrointestinal mucosa, support the microcirculation in the kidney and protect other organs from destruction. Among the many different selective cox-inhibitors of nsaids, meloxicam selectively inhibits cox-2, while nsaids such as diclofenac, piroxicam, and indometacin either similarly inhibit two cox-s, or inhibit cox-1 more than cox-2. However, meloxicam is relatively safe in the gastrointestinal tract and less toxic to the kidney, due to its weak inhibition of cox-1.

 

Indications:

It is suitable for symptomatic treatment of pain, swelling, soft tissue inflammation, traumatic pain and postoperative pain in rheumatoid arthritis and osteoarthritis.

 

 

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