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Pharmaceutical Raw Materials Procaine Base CAS 59-46-1 White Crystal Powder

Pharmaceutical Raw Materials Procaine Base CAS 59-46-1 White Crystal Powder

Pharmaceutical Raw Materials Procaine Base CAS 59-46-1 White Crystal Powder
Pharmaceutical Raw Materials Procaine Base CAS 59-46-1 White Crystal Powder

Large Image :  Pharmaceutical Raw Materials Procaine Base CAS 59-46-1 White Crystal Powder Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: P9461

Payment & Shipping Terms:

Minimum Order Quantity: 1kg
Price: $120-150/kg
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 800 kgs per year
Detailed Product Description
CAS No: 59-46-1 Molecular Formula: C13H20N2O2
Molecular Weight: 236.31 Density: 1.077g/cm3
Melting Point: 61 ° C Boiling Point: 373.6 ° C At 760 MmHg
Flash Point: 179.8 ° C Refractive Index: 1.542
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Pharmaceutical Raw Materials Procaine Base 59-46-1 Low Price Made In China

 

Basic parameter:

1. Product Name: Procaine

2. Product alias: benzoic acid, 4-amino -, 2 - (diethylamino) ethyl ester; 4-aminobenzoic acid, 2-diethylaminoethyl  ester; Procaine; Novocaine

3. CAS No.: 59-46-1

4. Molecular formula: C13H20N2O2

5. Molecular weight: 236.31000

6. Density: 1.077g/cm3

7. Melting point: 61 ° C

8. Boiling point: 373.6 ° C at 760 mmHg

9. Flash point: 179.8 ° C

10. Refractive index: 1.542

11. Properties: its hydrochloride is colorless, odorless, small needle like or lobular crystal, tastes slightly bitter, and its tongue tastes dull and numb. Soluble in water, slightly soluble in ethanol, slightly soluble in chloroform. Its aqueous solution is unstable, especially in light, acid and alkali substances are easy to deteriorate.

 

Certificate of Analysis:                                                     

ITEM

Procaine Base

BATCH NO

20190718

MF.G

2019/07/18

QUANTITY

300KG

STANDARD

Standard of Corporation

ITEM

INDEX

TEST

APPEARANCE

White to off-white Crystal powder

White Crystal powder

PURITY

≥98.0% 99.40%

LOSS ON DRYING

≤1.0% 0.45%

MELTING POINT

55-63℃ 58.0-59.5℃

RESULT

Confirms

ANALYST

 

 

CHECK

 

DATE

2019.07.26  

 

Structure:

Pharmaceutical Raw Materials Procaine Base CAS 59-46-1 White Crystal Powder 0

 

Pharmacological effects:
It is one of the commonly used local anesthetics. This drug is a local anesthetic of short acting esters with low lipophilicity and weak penetration of mucosa. Generally not used for surface anesthesia, local injection is often used for infiltration anesthesia, conduction anesthesia, subarachnoid anesthesia and epidural anesthesia. The drug started to take effect 1-3min after injection and could be maintained for 30-45min. The time could be prolonged by 20% after the addition of epinephrine. Procaine can be hydrolyzed by esterase in plasma and converted into p-aminobenzoic acid (PABA) and diethylaminoethanol. The former can resist the antibacterial effect of sulfonamides, so it should be avoided to be used with sulfonamides at the same time. Procaine can also be used for local closure of injury sites. Excessive use can cause central nervous system and cardiovascular reactions. Can cause allergic reaction sometimes, reason before use medicine should do skin allergy test, but skin test negative person still can produce allergic reaction. People who are allergic to this drug can be replaced by chlorprocaine and lidocaine.
 
Product features:
Procaine is a local anesthetic. It is commonly used clinically as a hydrochloride, also known as novocaine. White crystal or crystalline powder, soluble in water. Less toxic than cocaine. The injection can prolong the action time by adding trace epinephrine. For infiltration anesthesia, lumbar anesthesia, "closed therapy" and so on. In addition to the central nervous system and cardiovascular system reactions caused by overdose, skin allergy tests should be performed before medication if allergic reactions are occasionally observed. Its metabolite, p-aminobenzoic acid (PABA), can weaken the antibacterial effect of sulfonamides.
 
Indications:
1. It is mainly used for infiltration anesthesia.
2. For the operation of the lower abdomen, it will not take long. It can also be used for local intravenous anesthesia of limbs.
3. It is used for "blocking therapy" to treat certain injuries and inflammation, which can relieve the symptoms of the damaged and inflamed parts to a certain extent.
4. Used to correct vasomotor dysfunction in limbs.
5. Treat neurosis.
 

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