Pimobendan Medicine Raw Materials 74150-27-9 C19H18N4O2 Off White Powder

Chemical Properties White Solid

Originator Boehringer lngelhelm (Germany)

Uses antiviral

Uses Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of Pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of Pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction.

 

 

Veterinary Drugs and Treatments Pimobendan is used to treat dogs with congestive heart failure secondary to dilated cardiomyopathy or chronic mitral valve insufficiency (CMVI).

 

 

 

 

Description Pimobendan, a novel cardiotonic vasodilator, was introduced in Japan for the treatment of acute and mild to moderate chronic heart failure. It is a phosphodiesterase Ⅲ inhibitor and is able to enhance sensitization of myocardial contractile regulatory protein to calcium ions. The combination of these effects contribute to its inotropic activity. In patients with severe congestive heart failure, orally administered pimobendan improves cardiac index, stroke volume index, pulmonary wedge pressure, and systemic and pulmonary vascular resistance. Pimobendan is reported to be well tolerated and largely devoid of the proarrhythmic effects of classical phosphodiesterase Ill inhibitors. Studies also suggested that combination of the inotropic agent pimobendan with an ACE inhibitor such as enalapril may be superior to monotherapy for heart failure patients.

 

 

 

Wuhan dongkangyuan technology co., LTD is located in jiangxia district, wuhan city, hubei province. Main pharmaceutical intermediates, bulk drugs, food additives, antibiotics bulk drugs. Wuhan dongkangyuan technology co., LTD., located in wuhan, a thoroughfare of nine provinces, is a high-tech company specializing in the r&d and sales of chemical raw materials in central China. The company has its own research and development base, equipped with advanced production equipment and efficient and precise testing instruments, with a complete, scientific, quality management system. And constantly committed to technological innovation, product innovation and management innovation, with high and new technology and excellent innovative quality service to win the trust of the majority of users in institutions of higher learning, scientific research units, pharmaceutical manufacturers, quality inspection departments, environmental protection enterprises, chemical production, agricultural production, food-related industries. To ensure that our products in the industry with strong competitiveness. The company has independent import and export rights and excellent sales team. With the diligent efforts of all employees, the company has opened a wide market. The company's products sell well all over the country and exported to Europe, America, southeast Asia and Africa and other countries and regions, win the majority of customers unanimously recognized and praise. "Honesty and service first; Kang yuan produces, must belong to high-quality goods ". Integrity management, customer satisfaction is our consistent purpose; The pursuit of quality, to provide customers with high quality products is our bounden duty. Welcome customers patronage. Get the general customer's approval. The company adheres to the business philosophy of "ensuring first-class quality and maintaining first-class reputation", and adheres to the principle of "customer first" to provide high-quality services for our customers. Welcome to call to discuss business!