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Triamcinolone acetonide 76-25-5 skin care raw materials for the treatment of skin diseases

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Triamcinolone acetonide 76-25-5 skin care raw materials for the treatment of skin diseases

Large Image : Triamcinolone acetonide 76-25-5 skin care raw materials for the treatment of skin diseases Get Best Price

Product Details:

Place of Origin:	China
Brand Name:	DKY
Model Number:	76-25-5

Payment & Shipping Terms:

Minimum Order Quantity:	10g
Packaging Details:	1kg/bag or 100g/bag
Delivery Time:	5-7 work days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	800kg per year

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Detailed Product Description

CAS No:	76-25-5	Molecular Formula:	C24H31FO6
Molecular Weight:	434.5	EINECS No:	200-948-7
Melting Point:	274-278 ° C	Specific Rotation:	D23+109°(c=0.75inchloroform)
Boiling Point:	576.9±50.0°C	Density:	1.1517
Index Of Refraction:	1.5980	Storage Conditions:	Refrigerator
Solubility:	Very Slightly Soluble In Water, Slightly Soluble In Ethanol, Soluble In Chloroform, Slightly Soluble In Acetone.	Appearance:	White Or Almost White Crystalline Powder, Odorless, Bitter Taste.
High Light:	personal care raw materials , skin treatment chemicals

Triamcinolone acetonide 76-25-5 skin care raw materials for the treatment of skin diseases

Basic parameter:

1. Product name :Triamcinoloneacetonide

2. Product nicknames :KENALOG; ARISTODERM; 9 11 beta, alpha - FLUORO - 21 - DIHYDROXY - 16 alpha, 17 - ISOPROPYLIDENEDIOXY - 1, 4 - PREGNADIENE - 3, 20 - DIONE. 9 alpha - FLUORO - 16 alpha - HYDROXYPREDNISOLONE16ALPHA, 17 alpha - ACETONIDE; 9 alpha - FLUORO - 11 beta, alpha, 16 17 alpha, 21 - TETRAHYDROXY - 1, 4 - PREGNADIENE - 3, 20 - DIONE16, 17 - ACETONIDE; 9 - fluoro - 11 b, 16 a, 17, a 21 - tetrahydroxy - 1, 4 - pregnadiene - 3, 20 - dione16, 17 - acetonide; 9 a 16 - fluoro - a - hydroxyprednisolone16a, 17 a - acetonide; ALPHA - FLUORO - 11 beta, ALPHA, 16, 17, 21 - TETRA - HYDROXYPREGNA - 1, 4 - DIENE - 3, 20 - DIONE

3. CAS no. : 76-25-5

4. Molecular formula: C24H31FO6

5. Molecular weight: 434.5

6. EINECS no. : 200-948-7

7. Melting point: 274-278 ° C (dec)

8. Specific rotation: D23+109°(c=0.75inchloroform)

9. Boiling point: 576.9 + / - 50.0 ° C

10. Density: 1.1517

11. Index of refraction: 1.5980

12. Storage conditions: Refrigerator

13. Solubility: Practicallyinsolubleinwater, sparinglysolubleinethanol (96 percent).

14. Appearance: white or almost white crystalline powder, odorless, bitter taste.

15. Solubility: very slightly soluble in water, slightly soluble in ethanol, soluble in chloroform, slightly soluble in acetone.

Certificate of Analysis:

Product Name	Triamcinolone acetonide	Batch No.	20191210
MFG. Date	2019/12/10	Exp Date	2022/12/09
Quantity	50kg	Specification	USP36
ITEMS	SPECIFICATIONS		RESULTS
Appearance	White or almost white crystalline powder		White crystalline powder
Identification	A. Infrared absorption B. UV fraviolet absorption		Complies Complies
Specific Optical Rotation	+118^o～+130^o		+119.6^o
Related substance	The largest impurity≤0.3% Total impurity≤0.8%		The largest impurity0.14% Total impurity0.66%
Loss on drying	≤1.5%		0.39%
Heavy metals	≤25ppm		Complies
Assay	97.0%～102.0%		99.7%
Particle size	≤15um		11.4um
Congclusion	The product conforms to USP36

Structure:

Product overview:

Triamcinolone acetonide is A wide range of dermatology clinical application in our country A long-term glucocorticoid hormone drugs, also called QuAnShu loose, to inflammation ShuSong, corning, tong, connor cream, connor g - A, belong to the adrenal cortex hormones, for triamcinolone to inflammation (loose) derivatives, the role and triamcinolone are similar, have anti-inflammatory, anti-allergic, anti itch and shrinkage capillary effect, its water sodium retention effect is weak, and anti-inflammatory, anti-allergic effects than hydrocortisone (10 ~ 30 times), prednisone is strong and durable, aerosol inhalation in the treatment of bronchial asthma, the function is strong and durable. The local effect is better than trianxilong. Oral administration is easy to absorb. The oral dose was 5mg, with a bioavailability of about 23%, a peak blood concentration of 105ng/ml in 1 hour, and a half-life of 2 hours. The absorption of intramuscular injection is slow, it takes effect in a few hours, and the maximum effect is achieved in 1 ~ 2 days. The effect can be maintained for 2 ~ 3 weeks. Intradermal and intra-articular local injection of this drug is slow in absorption and lasts for a long time. Generally, the curative effect of a single injection can be maintained for more than 1 to 2 weeks. This drug has little binding to plasma albumin, which is metabolized into inactive metabolites in liver, kidney and tissue after absorption and excreted by kidney. Local injection can also show a lasting effect, ointment external use can also produce better efficacy. Triamcinolone acetonide is mainly used for clinical treatment of various skin diseases such as atopic dermatitis, contact dermatitis, seborrheic dermatitis, neurodermatitis, eczema, psoriasis, skin conditions such as psoriasis, flat lichen and skin pruritus, and bronchial asthma, rheumatoid arthritis, acute sprain, chronic lumbocrural pain, periarthritis of shoulder, tenosynovitis, eye inflammation, oral mucosal hyperemia, erosions, ulcers, granulomatous cheilitis, chronic infectious disease of the oral mucosa, can also be used for keloid, cystic acne, discoid lupus erythematosus (sle), and alopecia areata small damage of local injection. Triamcinolone acetonide acetate nasal spray can be used to prevent and treat perennial, seasonal allergic rhinitis and vasomotor rhinitis. Intra-articular injections can reduce inflammation and relieve pain, swelling or stiffness.

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