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White Crystalline Powder Allylestrenol 432-60-0 Estrogen Hormone Raw Material
Product Details:
Payment & Shipping Terms:
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Detailed Product Description
| CAS No: | 432-60-0 | Molecular Formula: | C21H32O |
|---|---|---|---|
| Molecular Weight: | 300.48 | EINECS No: | 207-082-9 |
| Melting Point: | 79.5-80 ° | Boiling Point: | 381.7 ° C |
| Density: | 0.9914 | Refractive Index: | 1.4800 |
| Flash Point: | 170.6 ℃ | Appearance: | White Crystalline Powder |
| Vapor Pressure: | 0.0±2.1 MmHg At 25℃ | Storage Conditions: | The Warehouse Is Ventilated, Low Temperature And Dry, Stored Separately From Food Materials |
| High Light: | api pharmaceuticals,pharmaceutical grade api intermediate |
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Allylestrenol 432-60-0 estrogen hormone raw material used in scientific research
Basic parameter:
1. Product name :Allylestrenol
2. Product nickname :orageston; Organon; ALLYLESTRENOL; 4 - ESTREN - 17 - ALPHA - ALLYL - 17 - BETA - OL; 13-17 - prop - methyl - 2 - enyl - 2,3,6,7,8,9,10,11,12,14,15,16 - dodecahydro - 1 h - cyclopenta [a] phenanthren - 17 - ol; 17 - alpha - allyloestr - 4 - en - 17 - beta - ol; 17 - Allylestr - 4 - en - 17 beta ol; 17 alpha Allyl - 17 beta hydroxy - D4 - estren
3. CAS no. : 432-60-0
4. Molecular formula: C21H32O
5. Molecular weight: 300.48
6. EINECS no. : 207-082-9
7. Melting point: 79.5-80 °
8. Boiling point: 381.7 ° C
9. Density: 0.9914
10. Refractive index: 1.48
11. Flash point: 170.6 ℃
12. Appearance description: white crystalline powder
13. Vapor pressure: 0.0±2.1 mmHg at 25℃
14. Storage conditions: the warehouse is ventilated, low temperature and dry, stored separately from food materials
Certificate of Analysis:
|
Product |
Allylestrenol |
Mfg. Date |
2019/12/21 |
|
Batch No. |
191221 |
Quantity |
25kg |
Retest Date |
2021/12 |
|
Standard |
In-house specification |
Packing Size |
25kg/drum |
|
Test |
Specification |
Result |
|
Characteristics |
White Or Creamy White Crystalline Powder |
white powder |
|
Specific Rotation |
+78°~ +83° |
+80.5° |
|
Loss on drying |
≤0.5% |
0.28% |
|
Related Substance |
Individual impurities |
Not more than 0.5% |
conforms |
|
Total impurities |
Not more than 1.0% |
0.4% |
|
Assay |
Between 97% and 103% |
99.6% |
|
Conclusion |
Complies with in-house specification |
Pharmacological significance:
The effect of allineol is several times that of progesterone, which can increase the endocrine activity of the placental trophoblastic layer, promote the secretion of endogenous progesterone and HCG, stimulate the dysfunctional placenta, and normalize the placental function. Meanwhile, the concentration and activity of oxytocin were increased, and the level of oxytocin in pregnant women was decreased. And antagonistic prostaglandin on the uterine stimulation, inhibit contractions so as to maintain pregnancy. This product has no effect of estrogen or androgen, and has no inhibitory effect of adrenal gland and gonadal gland.
Clinical indications:
Threatened abortion; Habitual abortion; Early preterm labor.
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