Yohimbine is an aphrodisiac health care product with 98% white powder, USP standard, good quality，65-19-0，C21H27ClN2O3

Yohimbine hydrochloride Usage And Synthesis

Chemical Properties Yohimbine hydrochloride is white to slightly yellow powder

Uses Indole alkaloid with α2-adrenergic blocking activity. Mydriatic. Used in the treatment of neurological disorders.

Uses alpha adrenergic blocker, mydriatic, antidepressant

Uses vasodilator, neuromodulator

Uses a2-adrenergic antagonist, used for erectile dysfunction

Uses Erectile dysfunction & Mydriatic agent

Uses An α2-adrenoceptor antagonist

Uses Pharmacological probe for the study of a2-adrenoceptor.

 

Yohimbinehydrochloride (molecular formula C21H26N2O3HCL, English yohimbine.) also known as weibeji, Yohimbinehydrochloride, yohimbine, yuleide tablet, yuleide, the appearance of white to milky white fine powder, slightly fragrant, bitter taste, melting point 288℃~290℃, soluble in chloroform, soluble in methanol, ethanol, slightly soluble in water. Plants derived from the dried bark of the wild African plant CorynanteYohimbe or extracts from the bark of the west African plant Chemicalbook. The pharmacological effect is to increase the sexual muscle tension, and the effect of urine inhibition is not harmful. Accelerate energy metabolism and increase energy supply. Clinical single dose for the treatment of male impotence and sexual dysfunction. The mechanism of action is to selectively block presynaptic norepinephrine receptors, promote the release of norepinephrine, release more norepinephrine from the nerve endings of the spongy body, reduce penile venous reflux, facilitate congestion and erection, and increase sexual fluid secretion. When a few apply, can make can pudendal swell, stimulate spinal cord to erect center and make sexual function is hyperactive.

 

 

 

Yohimbine hydrochloride pure white powder, slightly soluble in water, soluble in ethanol, chloroform, thermobenzene, slightly soluble in ether. Yohimbine extracted from yohimbine bark of Ghana can effectively improve male sexual dysfunction. It has been reported that the mixed yohimbine content in dried PansinystaliaYohimba bark is up to 6.1%.

 

 

Yohimbine hydrochloride is a preganglionic adrenergic nerve 2 receptor blocker that dilates peripheral blood vessels like reserpine, but weakly and briefly. The effect on the peripheral nervous system is to enhance parasympathetic and reduce sympathetic effect. By dilating the penis artery, the spongy body increases blood flow and makes it congested and erect. Yohimbine has been found to have a wide range of pharmacological activities, and plant derived yohimbine has been used as an over-the-counter drug to treat a variety of diseases. In the late 1980s, yohimbine and yohimbine hydrochloride were approved by the U.S. food and drug administration as prescription drugs for male sexual dysfunction.

 

Yohimbine pharmacological effects mainly include selective serotonin receptor blocking diameter and adrenaline receptors and adrenaline receptor is associated with the central mechanism of erectile function, yohimbine by selectively blocking ganglion presynaptic receptors, makes the brain cell is excited, the blood free methoxy the base of the benzene ethylene glycol (power, expansion of vascular smooth muscle, increase peripheral parasympathetic nervous tension, reduce the sympathetic nervous tension, thus expanding Yin artery, increasing the flow of blood to the Yin lotus cavernous sinus to fully erect but overdose of yohimbine can bring inhibition effect instead.