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Tianeptine Sodium CAS No 30123-17-2 Antidepressant API Intermediates

Tianeptine Sodium CAS No 30123-17-2 Antidepressant API Intermediates

Tianeptine Sodium CAS No 30123-17-2 Antidepressant API Intermediates
Tianeptine Sodium CAS No 30123-17-2 Antidepressant API Intermediates

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Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: 30123-17-2

Payment & Shipping Terms:

Minimum Order Quantity: 1g
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 200 kgs per year
Detailed Product Description
CAS No: 30123-17-2 Molecular Formula: C21H24ClN2NaO4S
Molecular Weight: 458.93 Density: 1.38 G/cm3
Melting Point: 180 ℃ Boiling Point: 609.2 C At 760 MmHg
Flash: DHS 322.2 ℃ Content: 99%
Packaging: 1KG/ Aluminum Foil Bag Detachable Appearance: White Or Light Yellow Powder, Easy To Wet.
Solubility: Soluble In Water, Methanol And Dichloromethane Storage: Low Temperature, Dry And Dark.
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Tianeptine sodium 30123-17-2 Active Pharmaceutical Ingredients antidepressant

 

Basic parameter:

1. Product name :Tianeptinesodiumsalt

2. Other names: s-1574; Stablon; TIANEPTINESODIUM; CoaxilsodiuMsalt; TIANEPTINESODIUMSALT; Tianeptinesodiumsalthydrate; (54317-11-2) tianeptinesodiumsalt; Tianeptinesodiumsalt; Sodium7 - (3 - chloro - 6, 10 - dihydro - - methyldibenzo (c, f) (1, 2) thiazepin - 11 - yl) amino) heptanoates, s - dioxide; Sodium7 - [(3 - chloro - 6, 10 - dihydro - - methyldibenzo [c, f] [1, 2] thiazepin - 11 - yl) amino] heptanoateS, S - dioxide

3. CAS no. : 30123-17-2

4. Molecular formula: C21H24ClN2NaO4S

5. Molecular weight: 458.93

6. Density: 1.38 g/cm3

7. Melting point: 180 ℃

8. Boiling point: 609.2 C at 760 mmHg

9. Flash: DHS 322.2 C

10. Content: 99%

11. Packaging: 1KG/ aluminum foil bag detachable

12. Appearance: white or light yellow powder, easy to wet.

13. Solubility: soluble in water, methanol and dichloromethane

 

Structure:

Tianeptine Sodium CAS No 30123-17-2 Antidepressant API Intermediates 0

 

 

Pharmacological effects:
Thianaputin sodium is a tricyclic antidepressant. Its antidepressant mechanism is different from that of traditional tricyclic antidepressants. It can increase the reuptake of 5-ht in the synaptic gap and may have the effect of improving the neuronal conduction of 5-ht. No affinity for choline or adrenaline receptors. Antidepressant efficacy was similar to tricyclic, but better tolerated than tricyclic. In animal experiments, it can increase the spontaneous activity of pyramidal cells in the hippocampus and accelerate the recovery of their functions after inhibition. Increased serotonin reuptake by neurons in the cerebral cortex and hippocampus. Thianapur sodium is absorbed rapidly and completely in the digestive tract. The distribution was rapid, with a PPB of up to 94%. The metabolism of the liver is complete through the hypo-oxidation and n-demethylation, and the terminal t1/2 is short, which is 2.5h. A very small amount of the protodrug (8%) is excreted from the kidneys, mainly its metabolites from the urine. Clearance of t1/2 was prolonged for 1h in patients with renal insufficiency.
 
Indications:
It is used to treat mild, moderate or major depression, neurogenic and reactive depression, anxiety depression with somatic, especially gastrointestinal distress, and anxiety depression in alcohol-dependent patients during withdrawal.

 

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