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78628-80-5 Terbinafine Hydrochloride API / Skin Antifungal Agents USP Standard

78628-80-5 Terbinafine Hydrochloride API / Skin Antifungal Agents USP Standard

78628-80-5 Terbinafine Hydrochloride API / Skin Antifungal Agents USP Standard
78628-80-5 Terbinafine Hydrochloride API / Skin Antifungal Agents USP Standard

Large Image :  78628-80-5 Terbinafine Hydrochloride API / Skin Antifungal Agents USP Standard Get Best Price

Product Details:

Place of Origin: china
Brand Name: DKY
Certification: GMP
Model Number: usp

Payment & Shipping Terms:

Minimum Order Quantity: KG
Packaging Details: 25kg cardboard barrel
Delivery Time: 1 DAYS
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 3000KG
Detailed Product Description
Product Standard: USP Pharmacopoeia Purpose: Skin Antifungal Agents
Cas No.: 78628-80-5 Appearance: White Powder
High Light:

disinfectant powder

,

bactericidal raw material

CAS: 78628-80-5/Terbinafine Hydrochloride API/Skin antifungal agents/USP standard/ 99% content
 
Product Name: Terbinafine Hydrochloride
Synonyms: lamosil;n-(6,6-dimethyl-2-hepten-4-ynyl)-n-methyl-1-naphthalenemethanamin(e)-1-naphthalenemethanaminmon;N-[(E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine Hydrochloride;Lamisil, N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1-naphthalenemethanamine;1-Naphthalenemethanamine, N-(2E)-6,6-dimethyl-2-hepten-4-ynyl-N-methyl-, hydrochloride;TERNBINAFINEHCL;({[(2E)-6,6-Dimethylhept-2-en-4-yn-1-yl](methyl)amino}methyl)naphthalene hydrochloride;Trebinafine hydrochloride
CAS: 78628-80-5
MF: C21H26ClN
MW: 327.89
EINECS: 616-640-4
 
Dermatologist Broad-spectrum Antifungal Drugs Terbinafine hydrochloride is a kind of broad-spectrum dermatologist allyl amine antifungal drugs. It is developed by Swiss Novartis in the 1980 s, and appeared in the market of UK for the first time in 1991. Approved by FDA of the United States for OTC drugs in 1996, and appeared in the market of the United States in the same year. At present, the drug is been sold in more than 90 countries of the word. It can specificity trouble the late biological decomposition of fungus sterol, selectively inhibit the activity of fungal squalene ring oxidase, and inhibit the squalene epoxidation in the formation of ungal cell membrane, thus to kill or inhibit the active of the fungus. Suitable for treatment of candidiasis skin, such as tinea manuum, tinea, tinea, ringworm of the body, tinea versicolor, it is also the best medicine for the treatment of onychomycosis.
Terbinafine hydrochloride entered the the first batch of country announced OTC directory in 2000. This product belongs to antifungal drugs. It has strong effect on shallow fungal infection, and can cure most of the fungal skin diseases through external use.
 
Chemical Properties White crystalline powder. Melting point is 204-208 oC.
Usage Terbinafine hydrochloride is a kind of broad-spectrum dermatologist allyl amine antifungal drugs. It has a significant effect on all kinds of tinea diseases , including fungus, trichophyton, ringworm of the body, tinea, tinea versicolor and onychomycosis caused by dermophyte. It can also be used for bronchial asthma,
 
Description Terbinafine hydrochloride is the first orally active allylamine antifungal with 30-fold greater antifungal activity than naftifine. The compound is indicated for the treatment of ringworm and fungal nail infections. Terbinatine hydrochloride acts on a single fungal enzyme, squalene epoxidase, interfering with the biosynthesis of ergosterols in cell membranes. Unlike other antifungal agents, it does not inhibit cytochrome P450 enzymes.
Chemical Properties Crystalline Powder
 
Uses An orally active, antimycotic allylamine related to Naftifine. A specfic inhibitor of squalene epoxidase, a key enzyme in fungal ergosterol biosynthesis. Antifungal.
Uses Terbinafine hydrochloride is a synthetic allylamine antifungal. It is used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch. It is used in adsorption, partition and stability studies.
Definition ChEBI: A hydrochloride obtained by reaction of terbinafine with one molar equivalent of hydrogen chloride.
 
 
Clinical Use (E)-N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene-methanamine hydrochloride (Lamisil) is an off-whitecrystalline material that is soluble in polar organic solventssuch as methanol, ethanol, and methylene chloride but isonly slightly soluble in water. The highly lipophilic freebase is insoluble in water. Terbinafine hydrochloride isavailable in a 1% cream for topical administration for thetreatment of tinea pedis, tinea corporis, and tinea cruris.Terbinafine is more potent than naftifine and has alsodemonstrated oral activity against onychomycosis (ringwormof the nails).
 
 

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