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99% Purity Pharmaceutical Raw Materials Chloramphenicol 56-75-7 White Powder
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Detailed Product Description
| CAS Number: | 56-75-7 | Molecular Formula: | C11H12Cl2N2O5 |
|---|---|---|---|
| Molecular Weight: | 323.1294 | EINECS No: | 200-287-4 |
| Melting Point: | 148-150 ° C | Specific Rotation: | 19.5º(c=6,EtOH) |
| Boiling Point: | 644.9±55.0°C | Density: | 1.6682 |
| Index Of Refraction: | 20°(C=5,EtOH) | Flash: | 14 ° C |
| Storage Conditions: | 2-8°C | Appearance: | White Or Yellowish With Green Needle-like Crystals. |
| Solubility: | Slightly Soluble In Water (2.5mg/ml, 25℃), Slightly Soluble In Propylene Glycol (150.8mg/ml), Easily Soluble In Methanol, Ethanol, Butanol, Ethyl Acetate, Acetone, Insoluble In Ether, Benzene, Petroleum Ether, Vegetable Oil. | USES: | Used To Treat Infections Caused By Typhoid, Dysentery, Escherichia Coli, Influenza, Brucella, Pneumococcus, Etc. |
| High Light: | pharma raw material,raw materials for medicines |
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Supply of CAS: 56-75-7 Chloramphenicol drugs API Manufacturer
Basic parameter:
1. Product name: chloramphenicol
2. Product alias: 2, 2-dichloro-n -[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]acetamide; D - (-) - - p - nitrophenyl threo - 1-2 - dichloracetamido - 1, 3 - propanediol; Mychel; Chloroamphenicol; CAF. Chloramphenicol.
3. EINECS no: 200-287-4
4. Molecular formula: C11H12Cl2N2O5
5. Molecular weight: 323.1294
6. CAS number: 56-75-7
7. Melting point: 148-150 ° C (lit.)
8. Specific rotation: 19.5 (c=6,EtOH)
9. Boiling point: 644.9 + / - 55.0 ° C (Predicted)
10. Density: 1.6682 (roughestimate)
11. Index of refraction: 20°(C=5,EtOH)
12. Flash: 14 ° C
13. Storage conditions: 2-8°C
14. Appearance: white or yellowish with green needle-like crystals.
15. Solubility: slightly soluble in water (2.5mg/ml, 25℃), slightly soluble in propylene glycol (150.8mg/ml), easily soluble in methanol, ethanol, butanol, ethyl acetate, acetone, insoluble in ether, benzene, petroleum ether, vegetable oil.
16. USES: used to treat infections caused by typhoid, dysentery, escherichia coli, influenza, brucella, pneumococcus, etc.
Certificate of Analysis:
| Product Name | Chloramphenicol | Batch No. | 20190805 | ||
| MFG. Date | Aug 05,2019 | Exp. Date | Aug 04,2021 | ||
| Quantity | 250kg | Batch size | 25kg | ||
| Test Items | Specifications | Results | |||
| Characteristics | Fine white or grayish white or yellowish white needle-like crystals or elongated plates | Yellowish whie needle-like crystals or elongated plates | |||
| Identification | Positive | Positive | |||
| Melting Point | 149～153oC | 150.0-152.3oC | |||
| Assay | 98.5～102% | 99.6% | |||
| Loss on drying | ≤0.5% | 0.18% | |||
| Residue on Ignition | ≤0.10% | 0.06% | |||
| Acidity or Alkalinity(PH) | 5.0～7.5 | 5.30 | |||
| Specific Rotation | +18.5～+20.5o | +19.1o | |||
| Heavy Metals | ≤0.001% | ≤0.001% | |||
| Related Substances | The any secondary spot≤0.5% Total≤2.0% | The any secondary spot≤0.5% Total≤2.0% | |||
| Chloride | ≤0.005% | ≤0.005% | |||
| Crystallinity | Meets the requirements | Meets the requirements | |||
| Conclusion | The above product complies with the standard EP9.0/BP2013. | ||||
Structure:
Indications:
This product is fat-soluble and can inhibit the formation of peptide chains and prevent the synthesis of proteins. Belongs to the bacteriostatic agent, when the high concentration or on the product is highly sensitive to bacteria bactericidal action. The whole body application is suitable for typhoid fever, paratyphoid fever and other salmonella, fragile bacteroidetes infection. 1. Chloramphenicol is the first choice for typhoid and paratyphoid, and can be used for typhoid and salmonella infections. 2. For ampicillin resistant influenza B meningitis or pneumococcus, meningococcal meningitis, sensitive gram-negative bacterial meningitis in patients with allergy to penicillin. 3. For otogenic brain abscess with mixed infection of aerobe and anaerobe. 4. Severe anaerobe infection, such as fragile bacillus infection. 5. It can be used in combination with aminoglycosides to treat various infections caused by sensitive bacteria and other microorganisms, such as septicemia and pulmonary infection caused by influenzae, salmonella and other gram-negative bacteria. 6. It is used locally to treat superficial infections of eyes and ears caused by e. coli, influenza, klebsiella, staphylococcus aureus and hemolytic streptococcus. 7, rickettsia, mycoplasma, infection is also effective. 8. It was not effective against pseudomonas aeruginosa and serratia. 9. Chloramphenicol eye drops are used in the treatment of eye infections caused by sensitive bacteria, such as trachoma, conjunctivitis, keratitis and perilitis of the eyelid. 10. Local ear drops of this drug can be used to treat external otitis, acute and chronic otitis media caused by sensitive bacterial infection. This drug can also be used for patients with otitis and abscess after radical mastoidectomy.
USES:
1. As a broad-spectrum bacteriostasis antibiotic, it is the first choice for the treatment of typhoid fever and paratyphoid fever. It is one of the special drugs for the treatment of anaerobic bacteria infection, and is used for the treatment of various infectious diseases caused by sensitive microorganisms. As a result of serious adverse reactions are used less and less.
2. The antibacterial spectrum, function and use are the same as chloramphenicol
3. For the treatment of infections caused by typhoid, dysentery, escherichia coli, influenza, brucella, pneumococcus, etc.
4. Antibiotic anti-infection API.
Contact Details
WuHan Dong Kang Yuan technology co., LTD
Contact Person: Angela
Tel: 86-15377658509
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