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99% Purity Tetracaine hydrochloride 136-47-0 Medicine Raw Materials white powder

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99% Purity Tetracaine hydrochloride 136-47-0 Medicine Raw Materials white powder

Large Image : 99% Purity Tetracaine hydrochloride 136-47-0 Medicine Raw Materials white powder Get Best Price

Product Details:

Place of Origin:	China
Brand Name:	DKY
Model Number:	136-47-0

Payment & Shipping Terms:

Minimum Order Quantity:	1kg
Packaging Details:	1kg/bag or 25kg/drum or 25kg/bag
Delivery Time:	5-7 work days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	50 tons per year

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Detailed Product Description

CAS No:	136-47-0	Molecular Formula:	C15H25ClN2O2
Molecular Weight:	300.82	EINECS No:	205-248-5
Melting Point:	149 ° C	Density:	1.1279
Index Of Refraction:	1.5200	Storage Conditions:	Refrigerator
Solubility:	Soluble In Water-soluble Water, Soluble In Ethanol.	Appearance:	White Crystalline Powder
High Light:	raw materials for drugs , pharmaceutical industry raw materials

99% Purity Tetracaine hydrochloride 136-47-0 Medicine Raw Materials white powder

Basic parameter:

1. Product name :Tetracainehydrochloride

2. Product alias :Tetracainehclpowder; CAS136-47-0 tetracainehydrochloridekf - wang (at) kf-chem.com. LANDOCAINHYDROCHLORIDE; INTERCAINHYDROCHLORIDE; MEETHOBALMHYDROCHLORIDE; 2 - (DIMETHYLAMINO) ETHYL4 - (N - BUTYLAMINO) BENZOATEHYDROCHLORIDE; 2 - DIMETHYLAMINOETHYLESTEROFP - BUTYLAMINOBENZOICACIDHYDROCHLORIDE; 4 - (N - BUTYLAMINO) BENZOICACID2 - (DIMETHYLAMINO) ETHYLESTERHYDROCHLORIDE

3. CAS no. : 136-47-0

4. Molecular formula: C15H25ClN2O2

5. Molecular weight: 300.82

6. EINECS no. : 205-248-5

7. Melting point: 149 ° C

8. Density: 1.1279 (roughestimate)

9. Index of refraction: 1.5200(estimate)

10. Storage conditions: Refrigerator

11. Solubility: alcohol: solublesoluble40partsofsolvent

12. Solubility: soluble in water-soluble water, soluble in ethanol.

13. Appearance: white crystalline powder

Certificate of Analysis:

Product Name	Tetracaine HCl	Batch No	190621
MFG. Date	2019/6/21	Test Date	2019/6/21
Exp. Date	2021/6/20	Test Standard	USP 36
Test Items	Specification			Test Results
Appearance	A white crystalling powder			Conforming
Identification	A,B,C in pass			Conforming
USP Reference standards	USP Tetracaine Hydrochloride RS. USP Endotoxin RS.			Conforming
Residual Solvents	Ethanol(Ⅲ)＜0.5%			0.16%
Sulphate Ash	/			/
Chromatographic purity	In pass			Conforming
Other requirements	In pass			Conforming
Acidity	In pass			Conforming
Loss on drying	≤2.0%			0.75%
Residue on ignition	≤0.10%			0.05%
Heavy metals	＜10ppm			4.9ppm
Assay	98.5%~101.0%			99.70%
Conclusion	Pass USP 36

Structure:

Summary:

Tetracaine hydrochloride is a highly effective local anesthetic that can revertively block nerve function. It is clinically used for infiltration anesthesia, nerve block anesthesia, epidural anesthesia, etc. Compared with procaine, its local anesthetic effect is significant, and it has been widely used in clinical practice. It is found that the synthesis of the intermediate p-aminobenzoic acid is a key step in the synthesis of tetracaine hydrochloride. Scientists improved the. In 1981, they proposed to synthesize p-aminobenzoic acid by alkylation of p-aminobenzoic acid with 1-bromobutane. However, this route was not suitable for industrial production due to the fact that it was impossible to avoid the formation of the by-products of p-aminobenzoic acid and the unstable nature of the raw material itself.

Indications:

Tetracaine hydrochloride is used for mucosal surface anesthesia, conduction anesthesia, epidural anesthesia and subarachnoid space anesthesia. For ophthalmic surface anesthesia, no constriction of blood vessels, no damage to corneal epithelium, no increase in intraocular pressure.

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