Arimidex 120511-73-1 Anastrozole Steroid Hormone Powder

Product Name: Anastrozole
CAS: 120511-73-1
MF: C17H19N5
MW: 293.36626
EINECS: 601-715-6

Anastrozole Chemical Properties
Melting point 81-82°C
Boiling point 469.7±55.0 °C(Predicted)
density 1.08±0.1 g/cm3(Predicted)
storage temp. Store at RT

This product is a potent and selective non-steroidal aromatase inhibitor. It can inhibit the conversion of androstenedione produced in the adrenal glands of postmenopausal patients into estrone, thereby significantly reducing the plasma estrogen level and inhibiting the growth of breast tumors. In addition, this product has no significant effect on the production of adrenal corticosteroids or aldosterone

Anastrozole, chemically known as 2,2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropiononitrile) a derivative of benzotriazole with the CAS registry number 120511-73-1, is a non-steroidal, third-generation achiral triazole derivative marketed as . It is one of the third-generation aromatase inhibitor which is a highly competitive and selective inhibitor of aromatase, thus blocking the conversion of testosterone into estradiol and androstenedione into estrone. Inhibition of the aromatase enzyme occurs particularly through competitive binding of aromatase to the hemegroup of cytochrome P450, decreasing estrogen biosynthesis in the peripheral tissues of the body and in the breast.