Payment & Shipping Terms:
|DeliveryTime:||Prompt||PackAge:||1kg Aluminum Foil Bag Or 25kg/drum，according To The Clients Requirement|
|Storage:||Store In Dry, Dark And Ventilated Place||LimitNum:||500 Gram Or 1 Kilogram|
|Transportation:||Air Or Ocean Or Rail Or Parcel Post（EMS、TNT、DHL、UPS、FEDEX），or According Your Requirement||Port:||Any Port In China|
|Assay:||99%||Shelf Life:||Two Years|
|Transport Package:||Discreet And Tight||Specification:||100% Qualified|
pharma raw material,
raw pharmaceutical materials
99%CAS19387-91-8 Drugs API Tinidazole pharmaceutical raw materials
1. Product Name: Tinidazole
2. Synonyms: TIMTEC-BB SBB006917;TINIDAZOLE;1-(2-(ethylsulfonyl)ethyl)-2-methyl-5-nitro-1h-imidazol;1-(2-(ethylsulfonyl)ethyl)-2-methyl-5-nitro-imidazol;1-(2-(ethylsulfonyl)-ethyl)-2-methyl-5-nitroimidazole;bioshik;cp12574;ethyl(2-(2-methyl-5-nitro-1-imidazolyl)ethyl)sulfone
3. CAS: 19387-91-8
4. MF: C8H13N3O4S
5. MW: 247.27
6. EINECS: 243-014-4
7. Tinidazole Usage And Synthesis
8. Chemical Properties solid
9. Usage Antiprotozoal (Trichomonas, Giardia); antiamebic; antibacterial.
10. Usage anticonvulsant
11. Usage anti-ulcerative
12. Usage For the treatment of trichomoniasis caused by T. vaginalis in both female and male patients. Also for the treatment of giardiasis caused by G. duodenalis in both adults and pediatric patients older than three years of age and for the treatment of intestin
Certificate of Analysis:
|Product name||Tinidazole||Batch no.|
|Appearance||Should be white to light yellow crystalline or crystalline powder, slightly bitter taste.||It is a light yellow crystalline powder with a slightly bitter taste.|
|Solubility||Meet the regulations|
|Identify||Should be positive.||positive|
|Should be positive.||positive|
|The infrared absorption spectrum of this product should be consistent with the control spectrum (spectrum set figure 665).||The infrared absorption spectra of this product should be consistent with those of the control.|
|Color of the solution||Should be positive.||positive|
|Loss on drying||≤0.5%||0.07%|
|Residue on ignition||≤0.1%||0.05%|
|Microbial limit test||Number of bacteria: ≤300 /g||positive|
|Mold and yeast: ≤60 / g||positive|
|E. coli: not to be detected||positive|
|The product was tested according to the second part of the 2010 edition of Chinese pharmacopoeia and the enterprise internal control standards, and the results were in accordance with the provisions.|
Tinidazole and metronidazole belong to nitroimidazoles. It has good activity to protozoa (amoeba lysate, trichomonas vaginalis, etc.) and anaerobe. The effect on amoeba and giardia ransii was superior to metronidazole. Gram-positive anaerobe (gastrococcus, streptococcus, lactobacillus), clostridium difficile and clostridium difficile were all sensitive to this product. This product is slightly more effective than metronidazole on gram-negative anaerobes such as fragile bacilli, fusobacteria and fischeri, while campylobacter jejuni is moderately sensitive to this product. Actinomycetes and propionibacterium were resistant to the drug. Its mechanism of action is to inhibit the pathogen DNA synthesis, and can quickly enter the cell.
This product is often used in combination with other anti-aerobic drugs for the treatment of sepsis, respiratory tract infection, abdominal and pelvic infection, unclean abortion and cellulitis caused by various anaerobic bacteria . Satisfactory results can be obtained. The product can also be used in combination with aminoglycosides and other antibiotics to prevent postoperative infection in surgical colon, rectal surgery, oral surgery and obstetrics and gynecology. The recovery rate of tinidazole in the treatment of trichomoniasis, giardia lamblia and amoebiasis was more than 90%. For the treatment of male and female urogenital trichomoniasis; Infections caused by sensitive anaerobe (such as bacteroides fragilis, other bacteroides, gastroenterococcus, clostridium difficile, clostridium difficile, etc.), such as pneumonia, pulmonary abscess and other respiratory tract infections, intraperitoneal infection, endometritis, tubal abscess and other gynecological infections, periodontitis, pericoronitis and other oral infections. Systemic and local infections for anaerobic bacteria, such as abdominal, gynecological, surgical wounds, skin and soft tissue, lung, thoracic and other site infections, as well as septicaemia, intestinal or urogenital trichomoniasis, piriform giardia, and intestinal and hepatic amoebiasis.
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