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Econazole Nitrate 24169-02-6 Raw Materials Used For Skin Antiseptic Ointment
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Detailed Product Description
| CAS No: | 24169-02-6 | Molecular Formula: | C18H16Cl3N3O4 |
|---|---|---|---|
| Molecular Weight: | 444.7 | EINECS No: | 246-053-5 |
| Melting Point: | 163 ~ 167℃ | Solubility: | The Product Is Soluble In Methanol, Slightly Soluble In Chlorine, And Slightly Dissolved In Water. |
| Appearance: | White Or Yellowish Crystal Or Crystalline Powder; Odourless. | Indications: | For Skin, Finger (toe) Nail Infections Caused By Dermatophytes, Yeasts And Other Fungi And Vaginal And Secondary Infections Caused By Yeast (e.g. Candida) And Gram-positive Bacteria. |
| High Light: | personal care raw materials,skin treatment chemicals |
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Econazole nitrate 24169-02-6 skin care raw materials used for skin antiseptic ointment
Basic parameter:
1. Product name :Econazolenitrate
2. Product alias :1-[2-(4-chlorobenzyl)oxy-2-(2,4-dichlorophenyl)ethyl]imidazole; 1 - [2 - [(4 chlorophenyl) methoxy] - 2 - (2, 4 - dichlorophenyl) baton rouge] imidazole; Econazolenitratesalt, 1 - (2 - [(4 Chlorophenyl) methoxy] - 2 - (2, 4 - dichlorophenyl] baton rouge) 1 h - imidazole; ECONAZOLENITRATE1 %; Econazole; Econazolenitrate (Spectazole); Gynoryl; 1 - (2 - (4 - chlorobenzyl foxy) - 2 - (2, 4 - dichlorophenyl) baton rouge) 1 h - iMidazolenitrate
3. CAS no. : 24169-02-6
4. Molecular formula: C18H16Cl3N3O4
5. Molecular weight: 444.7
6. EINECS no. : 246-053-5
7. Melting point: 163 ~ 167℃
8. Solubility: the product is soluble in methanol, slightly soluble in chlorine, and slightly dissolved in water.
9. Appearance: white or yellowish crystal or crystalline powder; Odourless.
10. Indications: for skin, finger (toe) nail infections caused by dermatophytes, yeasts and other fungi and vaginal and secondary infections caused by yeast (e.g. candida) and gram-positive bacteria.
11. Function: antifungal agent
12. Storage method: sealed package. Store in a cool, dry place.
Structure:
Pharmacological effects:
Riconazole nitrate is a pyrrole antifungal agent, which is a chlorination derivative of miconazole. It has antibacterial effects on candida, pigmentoides, coccidioides, histoplasmosis, spore filariae, etc., and also has antibacterial activities against tinea trichoderma. It has poor effects on aspergillus, schenkella, some melanosporaceae and trichoderma. By interfering with the activity of cytochrome P450, it inhibits the biosynthesis of ergosterol, the main sterol in the cell membrane of fungi, damages the cell membrane of fungi and changes its permeability, resulting in leakage of important intracellular substances. It can inhibit the biosynthesis of triacylglycerol and phospholipid of fungi, inhibit the activity of oxidase and peroxidase, and cause the accumulation of hydrogen peroxide in cells, leading to cell submicrostructure degeneration and cell necrosis. Candida albicans inhibited the transition from spores to invasive hyphae. It is suitable for tinea pedis, tinea pedis, tinea jock, tinea versicolor and dermatocandidiasis.
Contact Details
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Tel: 86-15377658509
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