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Isotretinoin is the most effective way to treat acne. Isotretinoin acts on all pathophysiological aspects of acne
Indications for the application of oral isotretinoin:
①Severe nodular cystic acne and its variant forms;
②Inflammatory acne with scar formation;
③ Moderate and severe acne that are ineffective to the following treatments: use combination therapy for 3 months, including those who use tetracyclines systemically;
④ Acne patients with severe psychological stress (disfigurement phobia);
⑤ Gram-negative bacilli folliculitis;
⑥ Those who frequently relapse and need repeated and long-term systemic antibiotics;
⑦ Few patients who need rapid recovery for some reason.
Dosage: The usual dose is 0.25～0.5 mg/(kg·d), in order to reduce adverse reactions, the dose should not exceed 0.5 mg/(kg·d). The course of treatment depends on the weight of the patient and the daily dose. The minimum cumulative dose is 60 mg/kg as the target, but if the cumulative dose reaches 60 mg/kg and the satisfactory effect is not achieved, it can be increased to 75 mg/kg. However, even if grade 1 acne is completely cleared, if you stop using isotretinoin before reaching the 60 mg/kg threshold, the probability of permanent cure will be significantly reduced.
Contact Person: Tim