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GMP Isotretinoin API Treat Severe Acne CAS 4759-48-2

GMP Isotretinoin API Treat Severe Acne CAS 4759-48-2

GMP Isotretinoin API Treat Severe Acne CAS 4759-48-2
GMP Isotretinoin API Treat Severe Acne CAS 4759-48-2 GMP Isotretinoin API Treat Severe Acne CAS 4759-48-2

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Product Details:

Place of Origin: HUBEI
Brand Name: DKY
Certification: GMP
Model Number: API

Payment & Shipping Terms:

Minimum Order Quantity: 10g
Price: USD650/KG
Packaging Details: 1kg aluminum foil bag
Delivery Time: 1days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 5000kg
Detailed Product Description
Exterior: Brownish Yellow Traits: Powder
CAS: 4759-48-2 MF: C20H28O2
High Light:

CAS 4759-48-2


Isotretinoin API


GMP Isotretinoin

Product Name: Isotretinoin
Synonyms: Tretinoin Impurity 1(Tretinoin EP Impurity A);Anti Acne Powerful Isotretinoin Powder Isotretinoin Pharmaceutical Raw Materials;Isotretinoin Capsules;Isotretinoin-D5/13-cis-Retinoic acid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;ISOTRETINON;A different diMension acid
CAS: 4759-48-2
MF: C20H28O2
MW: 300.44
EINECS: 225-296-0
Chemical Properties Yellow-Orange Crystalline Powder
Uses 5HT1a receptor agonist, anxiolytic
Uses isotretinoin is a retinoid derivative with improved bioavailability and percutaneous absorption for acne treatment products.
Uses Used as a treatment for severe acne. Presently being studied in conjuction with the treatment of photoaged skin.

Isotretinoin is the most effective way to treat acne. Isotretinoin acts on all pathophysiological aspects of acne

Indications for the application of oral isotretinoin:

①Severe nodular cystic acne and its variant forms;

②Inflammatory acne with scar formation;

③ Moderate and severe acne that are ineffective to the following treatments: use combination therapy for 3 months, including those who use tetracyclines systemically;

④ Acne patients with severe psychological stress (disfigurement phobia);

⑤ Gram-negative bacilli folliculitis;

⑥ Those who frequently relapse and need repeated and long-term systemic antibiotics;

⑦ Few patients who need rapid recovery for some reason.

Dosage: The usual dose is 0.25~0.5 mg/(kg·d), in order to reduce adverse reactions, the dose should not exceed 0.5 mg/(kg·d). The course of treatment depends on the weight of the patient and the daily dose. The minimum cumulative dose is 60 mg/kg as the target, but if the cumulative dose reaches 60 mg/kg and the satisfactory effect is not achieved, it can be increased to 75 mg/kg. However, even if grade 1 acne is completely cleared, if you stop using isotretinoin before reaching the 60 mg/kg threshold, the probability of permanent cure will be significantly reduced.


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