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Indometacin 53-86-1 pharmaceutical raw material used to reduce inflammation and relieve pain
Product Details:
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Detailed Product Description
| CAS Number: | 53-86-1 | EINECS No: | 200-186-5 |
|---|---|---|---|
| Molecular Formula: | C19H16ClNO4 | Molecular Weight: | 357.79 |
| Melting Point: | 155-162 ℃ | Boiling Point: | 499.4°C At 760 MmHg |
| Flash: | 255.8 ° C | Vapor Pressure: | 8.61E-11mmHg At 25°C |
| Properties: | White Or Yellowish Crystalline Powder. Almost Tasteless And Odorless. | Solubility: | Soluble In Acetone, Slightly Soluble In Ethanol, Ether, Chloroform And Methanol, Slightly Soluble In Benzene, Very Slightly Soluble In Toluene, Almost Insoluble In Water. Soluble In Sodium Hydroxide Solution. |
| High Light: | pharma raw material,raw materials for medicines |
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Indometacin 53-86-1 pharmaceutical raw material used to reduce inflammation and relieve pain
Basic parameter:
1. Product name: Indomethacin
2. Product alias: Indomethacin methanol solution; Indomethacin crystalline; Indomethacin usp. Indometacin. 1 - (4 - chlorobenzoyl) - 5-2 - methylindol - 3 - methoxy - ylacetic acid; {1 - [(4 chlorophenyl) carbonyl] - 5 - methoxy - 2 - methyl - 1 h - indol - 3 - yl} acetate
3. CAS number: 53-86-1
4. EINECS no. : 200-186-5
5. Molecular formula: C19H16ClNO4
6. Molecular weight: 357.79
7. Melting point: 155-162 ℃
8. Boiling point: 499.4°C at 760 mmHg
9. Flash: 255.8 ° C
10. Vapor pressure: 8.61E-11mmHg at 25°C
11. Properties: white or yellowish crystalline powder. Almost tasteless and odorless.
12. Solubility: soluble in acetone, slightly soluble in ethanol, ether, chloroform and methanol, slightly soluble in benzene, very slightly soluble in toluene, almost insoluble in water. Soluble in sodium hydroxide solution.
Certificate of Analysis:
| Product Name | Indomethacin | Batch No. | 200527 |
| MFG. Date | 2020.05.27 | Exp Date | 2022.05.26 |
| Quantity | 500.40kg | According to | BP2010 |
| ITEMS | SPECIFICATIONS | RESULTS | |
| Characteristics | White or yellow crystalline powder | Yellow crystalline powder | |
| Identification | |||
| A:Melting point | 158℃～162℃ | 160.0℃～162.0℃ | |
| C:Infrared Absorpt on spectrum | Meets the requirements | Meets the requirements | |
| Tests | |||
| Related substances | Meets the requirements | Meets the requirements | |
| Heavy metals | ≤20ppm | ＜20ppm | |
| Loss on drying | ≤0.5% | 0.05% | |
| Sulphated ash | ≤0.1% | 0.05% | |
| Assay | 98.5%～100.5% | 99.59% | |
| Particle Size | 80%particle less than 80um | Meets the requirements | |
| Conclusion | The above product conforms to BP2010 | ||
Structure:
USES:
1. This product has obvious anti-inflammatory and antipyretic effect, and is mainly used for rheumatic arthritis, ankylosing photospondylitis, osteoarthritis and so on, in which salicylic acid drugs are not easy to be tolerated or have no significant curative effect.
2. Non-hormonal anti-inflammatory and analgesic
3. Cyclooxygenase (COX) inhibitor, selectively inhibiting cox-1; Blocking the biosynthesis of prostatic cord. In medicine, anti-inflammatory, antipyretic effect is obvious, mainly used for salicylic acid drugs are not easy to tolerate or efficacy is not significant rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and so on.
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Contact Details
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Tel: 86-15377658509
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