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Lidocaine Hydrochloride Pharma Raw Materials For Anesthesia

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Lidocaine Hydrochloride Pharma Raw Materials For Anesthesia

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Product Details:

Place of Origin:	China
Brand Name:	DKY
Model Number:	73-78-9

Payment & Shipping Terms:

Minimum Order Quantity:	1 KG
Packaging Details:	1kg/bag or 25kg/drum
Delivery Time:	5-7 work days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	200 tons per year

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Detailed Product Description

CAS No:	73-78-9	EINECS No:	200-803-8
Molecular Formula:	C14H23ClN2O	Molecular Weight:	270.7982
Melting Point:	75-79 ℃	PH:	4.0 To 5.5
Moisture:	5.0% 7.5%	Incandescent Residue:	≤0.1%
Heavy Metal:	≤10ppm	Standard:	CP2010; USP
Solubility:	Soluble In Water Or Ethanol. The Aqueous Solution Is Stable Under Acid And Alkali, And Rarely Deteriorates After Repeated Autoclave Sterilization.	Appearance:	White Crystalline Powder, Odorless.
Appearance Description:	White Powder	Content:	99%
Packing:	25kg/ Cardboard Drum
High Light:	caine series chemicals , caine medicine raw material

Lidocaine HCl 73-78-9 Caine Series Pharma Raw Materials used for anesthesia

1. Product name :lidocaine

2. Product nickname :2-(dimethylamino-n -(2,6-dimethylphenyl)-acetamide; Lidocaine HCl. Lignocaine HCl. LidocaineHydrochloride; N - (2, 6 - dimethylphenyl) - N ~ 2 ~ N ~ 2 ~ - diethylglycinamide hydrochloride (1:1)

3. CAS: 73-78-9

4. EINECS: 200-803-8

5. Molecular formula: C14H23ClN2O

6. Molecular weight: 270.7982

7. Melting point: 75-79 ℃

8. Ph: 4.0 to 5.5

9. Moisture: 5.0% 7.5%

10. Incandescent residue: ≤0.1%

11. Heavy metal: ≤10ppm

12. Standard: CP2010; USP

13. Solubility: soluble in water

14. Appearance: white crystalline powder, odorless.

15. Solubility: soluble in water or ethanol. The aqueous solution is stable under acid and alkali, and rarely deteriorates 16. after repeated autoclave sterilization.

17. Appearance description: white powder

18. Content: 99%

19. Packing: 25kg/ cardboard drum

Certificate of Analysis:

Product Name	Lidocaine hydrochloride
Quantity	1kg		Batch No.		20200305
MFG. Date	20200305		Analysis Date		20200306
Exp. Date	20200305		Inspection Basis		USP35
ITEMS		SPECIFICATIONS		RESULTS
Appearance		White crystalline powder		Pass
Content Wt.		99.00%-101.00%		99.92%
Identification		Chloridate		Positive
		Test A		Positive
Melting point		74-79℃		76-78℃
Appearance of solution		Clear and colourless		Pass
Water		5.5-7.0%		6.7%
Acidity PH		4.0-5.5		5.2
Sulphated ash		0.10% max		0.08%
Heavy metals		5ppm max		Pass
2, 6-Dimethylaniline		100ppm max		Pass
Conclusion		Qualified

Structure:

Pharmacological effects:

Convulsions may occur when the blood concentration of the drug exceeds 5 ·ml-1. At a low dose, this product can promote the k+ outflow from cardiomyocytes, reduce the self-discipline of cardiomyocytes, and has an anti-ventricular arrhythmia effect. There was no significant effect on the electrical activity, atrioventricular conduction and myocardial contraction of cardiomyocytes at the therapeutic dose. A further increase in the concentration of the drug may cause a slowing of cardiac conduction velocity, atrioventricular block, inhibition of myocardial contractility, and a decrease in cardiac output.

Indications:

It is a local anesthetic and an antiarrhythmic agent. It is mainly used for infiltration anesthesia, epidural anesthesia, surface anesthesia (including mucosal anesthesia during thoracoscopy or abdominal surgery) and nerve block. This product can be used for ventricular premature beats and ventricular tachycardia after acute myocardial infarction, as well as digitalis poisoning, cardiac surgery, and ventricular arrhythmias caused by cardiac catheters. It is usually ineffective against supraventricular arrhythmias.

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