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Metronidazole 443-48-1 Pharmaceutical Raw Material Used To Fight Infection

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Metronidazole 443-48-1 Pharmaceutical Raw Material Used To Fight Infection

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Product Details:

Place of Origin:	China
Brand Name:	DKY
Model Number:	443-48-1

Payment & Shipping Terms:

Minimum Order Quantity:	1kg
Packaging Details:	1kg/bag or 25kg/drum or 25kg/bag
Delivery Time:	5-7 work days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	800 tons per year

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Detailed Product Description

CAS No:	443-48-1	Molecular Formula:	C6H9N3O3
Molecular Weight:	171.15400	Appearance:	White To Slightly Yellow Crystalline Powder
Density:	1.45g /cm2	Melting Point:	159-161 °C
Boiling Point:	405.4ºC At 760 MmHg	Flash:	199ºC
Index Of Refraction:	1.612	Stability:	Stability. Incompatible With Strong Oxidants.
Vapor Pressure:	2.67E-07mmHg At 25°C	Solubility:	Soluble In Water (1:100), Ethanol (1:200), Chloroform (1:250), Slightly Soluble In Ether, Insoluble In Dimethyl Formyl Ammonia, Soluble In Inorganic Acids.
High Light:	raw materials for drugs , medicine chemicals

Metronidazole 443-48-1 pharmaceutical raw material used to fight infection

Basic parameter:

1. Product name: metronidazole

2. Product alias: 2-methyl-5-nitroimide-1-ethanol; Eumin; Bexon; Klont; 1 h - Imidazole - 1 - ethanol, 2 - methyl - 5 - nitro -; Metronidazole. Atrivyl; Clont; FLACYL; Klion; Meronidal; Thivazol

3. CAS no. : 443-48-1

4. Molecular formula: C6H9N3O3

5. Molecular weight: 171.15400

6. Appearance: white to slightly yellow crystalline powder

7. Density: 1.45g /cm2

8. Melting point: 159-161 °C(lit.)

9. Boiling point: 405.4 C at 760 mmHg

10. Flash: 199 DHS C

11. Index of refraction: 1.612

12. Stability: stability. Incompatible with strong oxidants.

13. Storage conditions: 2-8 C

14. Vapor pressure: 2.67E-07mmHg at 25°C

15. Solubility: soluble in water (1:100), ethanol (1:200), chloroform (1:250), slightly soluble in ether, insoluble in dimethyl formyl ammonia, soluble in inorganic acids.

Certificate of Analysis:

Product Name	Metronidazole		Batch Weight		500kgs
Batch No	190820		Analysis Date		Aug.20, 2019
MFG. Date	Aug.20, 2019		Exp. Date		Aug.20, 2023
Characteristics	A white or yellowish crystalline powder, slightly soluble in water, in acetone, in alcohol and in methylene, chloride, very slightly soluble in ether.
Packing	Well-closed fiber drum with sealed double polyethylene bag, net capacity 25kgs.
Storage	Preserve in a well-closed containers, protected from light.
The goods have already passed microorganism test, no any other extraneous matter.
Test Items		Specification		Test Results
Identifications		A:IR B:UV		Comply
Melting point		159～163℃		160.4～160.7℃
Loss on drying		0.5% Max		0.23%
Residue on ignition		0.1% Max		0.06%
Heavy metals		0.005% Max		＜0.005%
Non-basic substances		Comply		Comply
Chromatographic purity		Comply		Comply
Residual solvents		Comply		Comply
Assay		99.0%-101.0% C₆H₉N₃O₃		99.36% C₆H₉N₃O₃
Conclusion		Comply with the requirement of USP27 standard

Structure:

Metronidazole 443-48-1 Pharmaceutical Raw Material Used To Fight Infection 0

Indications:

Nitroimidazole derivatives. It has strong antimicrobial activity against anaerobe, trichomonas, amoeba and giardia lamblia. For: 1. Mixed infection of various aerobic bacteria and anaerobic bacteria, including abdominal cavity and pelvic cavity infection, lung abscess, brain abscess, etc., but it is usually required to be used together with anti-aerobic antibacterial drugs. 2. Oral administration can be used for pseudomembranous enteritis, hp-related gastritis, periodontal infection and gardnerella vaginitis caused by c. difficile, etc., which is the first choice for the treatment of vaginal trichomoniasis. 3. Treatment of intestinal and parenteral amoebiasis, vaginal trichomoniasis, dracunculiasis, giardia, and colonic ciliopathy. 4. It can be used in combination with other antibacterial drugs for the prevention of pelvic, intestinal and abdominal operations.

USES:

1. This product has been used for the treatment of vaginal trichomoniasis since 1959, and has been used for intestinal and external amoebiasis since 1970, with high efficacy, low toxicity and wide application. It has mutagenic and teratogenic effects on animal experiments.

2. Strong antibacterial action against most anaerobic bacteria.

3. For the treatment of amoebiasis, trichomoniasis and anaerobe infection.

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