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Prilocaine Cas 721-50-6 Pharma Grade White Crystalline Powder For Relieve Pain

Prilocaine Cas 721-50-6 Pharma Grade White Crystalline Powder For Relieve Pain

Prilocaine  Cas 721-50-6 Pharma Grade White Crystalline Powder For Relieve Pain
Prilocaine  Cas 721-50-6 Pharma Grade White Crystalline Powder For Relieve Pain

Large Image :  Prilocaine Cas 721-50-6 Pharma Grade White Crystalline Powder For Relieve Pain Get Best Price

Product Details:

Place of Origin: China
Brand Name: DKY
Model Number: 721-50-6

Payment & Shipping Terms:

Minimum Order Quantity: 100g
Packaging Details: 1kg/bag or 25kg/drum
Delivery Time: 5-7 work days
Payment Terms: T/T, Western Union, MoneyGram
Supply Ability: 20 tons per year
Detailed Product Description
CAS No: 721-50-6 Molecular Formula: C13H20N2O
Molecular Weight: 220.31 EINECS No: 211-957-0
Flash Point: 134.3±23.3 ℃ Melting Point: 37-38 °
Boiling Point: Bp0.1159-162 ° Density: 1.0117 (roughestimate)
Vapor Pressure: 0.0± 0.8mmhg At 25℃ Index Of Refraction: ND201.5298
Solubility: Soluble In Water And Ethanol, Slightly Soluble In Chloroform. Taste Sour Bitter, No Smell. Appearance: White Crystalline Powder.
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Prilocaine 721-50-6 Caine Series Pharma Raw Materials used to relieve pain

 

Basic parameter:

1. Product name :Prilocaine

2. Product alias :astra1515; Citanest; L67; L67; N - (2 - methylphenyl) - 2 - (propylamino) - propanamid; O - Methyl - 2 - propylaminopropionanilide; O - Methyl - alpha - propylaminopropionanilide; O - Propionotoluidide, 2 - (propylamino) -

3. CAS no. : 721-50-6

4. Molecular formula: C13H20N2O

5. Molecular weight: 220.31

6. EINECS no. : 211-957-0

7. Flash point: 134.3±23.3 ℃

8. Melting point: 37-38 °

9. Boiling point: bp0.1159-162 °

10. Density: 1.0117 (roughestimate)

11. Vapor pressure: 0.0± 0.8mmhg at 25℃

12. Index of refraction: nD201.5298

13. Solubility: Slightly soluble in water, very soluble in acetone and in ethanol (96 per cent).

14. Appearance: white crystalline powder.

 

Certificate of Analysis:

Product

PRILOCAINE base

batch No.

190430

Mfg. date

2019-04-30

Approval Date

2019-05-01

Exp. date

2019-04-29

Tests

Results

Specifications

Description

White crystalline powder

White or almost white crystalline powder

Solubility

Complies

Very soluble in alcohol and in acetone; slightly soluble in water.

Identification

Complies

By IR, to match with the working standard

Melting point

36.9℃~38.5℃

36℃~39℃

Water

0.04%

≤0.5%

Residue on ignition

0.03%

≤0.1%

Related compound A

Complies

≤0.01%

Related compounds

0.05%

not more than 0.2% of any individual impurity

 

Complies

not more than one impurity exceeds 0.1%

 

0.15%

not more than 0.5% of total impurities

Residual solvents

Not detected

Dichloromethane Not more than0.06%

 

Not detected

Ethanol Not more than0.5%

 

0.03%

Isopropyl ether Not more than0.5%

Assay

99.27%

≥99.0%

Conclusion : Conforms to USP39

 

Structure:

Prilocaine  Cas 721-50-6 Pharma Grade White Crystalline Powder For Relieve Pain 0

 

Pharmacological effects:
The local anaesthesia effect of 3% solution was similar to that of 2% lidocaine plus epinephrine, and the effect was slow, about 6 ~ 7min, and the maintenance time was about 1.5 ~ 2h, with strong penetration of mucosa. Epinephrine slightly prolongs activity. The PPB is 55%, and t1/2 is about 1.5h. Metabolism in the liver, its metabolite nitrotoluidine can oxidize hemoglobin, forming methemoglobin. Can be transported to the fetus via the placenta.
 
Application:
Local anesthetic. The drug effect is better than procaine, the strength and speed of local anesthesia is similar to lidocaine, but the effect time is longer, the toxicity is smaller, because the metabolism is fast, the accumulation is smaller. It is suitable for epidural anesthesia, conduction anesthesia and infiltration anesthesia.
 
 

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