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Estrone 53-16-7 Estrogen Hormone Raw Material

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Estrone 53-16-7 Estrogen Hormone Raw Material

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Product Details:

Place of Origin:	China
Brand Name:	DKY
Model Number:	53-16-7

Payment & Shipping Terms:

Minimum Order Quantity:	10g
Packaging Details:	1kg/bag or 25kg/drum
Delivery Time:	5-7 work days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	1000kg per year

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Detailed Product Description

CAS Number:	53-16-7	Molecular Formula:	C18H22O2
Molecular Weight:	270.37	EINECS No:	200-164-5
Properties:	White Crystalline Powder, Soluble In Ethanol, Insoluble In Water.	Density:	1.164 G/cm3
Melting Point:	258-261 ℃	Boiling Point:	445.2°C At 760 MmHg
Flash:	189.7 ° C	Water Solubility:	0.03 G/L
Vapor Pressure:	1.54E-08mmHg At 25°C	Specific Rotation:	158 ℃
Heavy Metal:	≤0.03.0 PPM	Content:	≥ 98.5%
Purpose And Description:	Research Reagent, Widely Used In Molecular Biology, Pharmacology And Other Scientific Research.	Storage Conditions:	Room Temperature, Keep Away From Light, Moisture, Airtight And Dry.
High Light:	female hormones estrogen , women hormones estrogen

Estrone 53-16-7 estrogen hormone raw material for women's health

https://mao.ecer.com/photo/activepharmaingredient/document/17909/Estrone%20test%20method%28USP39%29.pdf

Basic parameter:

1. Product name: Estrone

2. Product alias: 1,3,5(10)-estratrien-3-ol-17-one; 3 beta -,3,5 Hydroxyestra - 1 (10) -- trien - 17 - one; 3 - Hydroxy - 1,3,5 (10) -- estratrien - 17 - one; Beta - Estrone; ,3,5 Estra - 1 (10) -- trien - 17 - one, 3 - hydroxy -; Estrol; Folliculin; Ketohydroxyestrin; Oestrin; Oestrone; ; 3 -,3,5 hydroxyestra - 1 (10) -- trien - 17 - one; (13 8 r, s) - 3 - hydroxy - 13 - methyl - 7,8,9,11,12,14,15,16 octahydro - 6 - h - cyclopenta [a] phenanthren - 17 - one

3. CAS number: 53-16-7

4. Molecular formula: C18H22O2

5. Molecular weight: 270.37

6. EINECS: 200-164-5

7. Properties: white crystalline powder, soluble in ethanol, insoluble in water.

8. Density: 1.164 g/cm3

9. Melting point: 258-261 ℃

10. Boiling point: 445.2°C at 760 mmHg

11. Flash: 189.7 ° C

12. Vapor pressure: 1.54E-08mmHg at 25°C

13. Specific rotation: 158

14. Water solubility: 0.03 g/L

15. Heavy metal: ≤0.03.0 PPM

16. Content: ≥ 98.5%

17. Purpose and description: research reagent, widely used in molecular biology, pharmacology and other scientific 18. research.

19. Storage conditions: room temperature, keep away from light, moisture, airtight and dry.

Certificate of Analysis:

Product Name	Estroene	Batch No	20191012
Batch Size	10.0kg	Quantity	5.0kg
MFG. Date	2019/10/12	Test Date	20191012
Exp. Date	2021/10/11	Standard	USP36

Test Items	Specification	Test Results
Appearance	A white or almost white crystalline powder	conform
Identification	TLC	conform
	UV Spectrum	conform
	IR Spectrum	conform
Clarity of solution	The solution is clear	conform
Specific optical rotation	+158°~+165°	+162°
Loss on drying	≤0.5%	0.21%
Residue on ignition	≤0.5%	0.11%
Limit of equenin and equilin	Meet the requirements	conform
Ordinary impourities	Meet the requirements	conform
Residual solvents	Meet the requirements	conform
Sulphated ash	NMT0.2%	0.04%
Assay	97.0%~103.0%	99.30%

Conclusion

This batch complies with USP36.

Structure:

Product details:

White to milky crystalline powder, odorless, tasteless, melting point 280℃ (decomposition), specific curl +158. ~ + 165. Dioxane. Almost insoluble in water, soluble in ethanol, chloroform, boiling ethanol, acetone, oxane, vegetable oil, slightly soluble in anhydrous ethanol, ether, lye. Estrone is a kind of estrogen secreted by mature ovarian follicles (mainly follicular membrane cells) and corpus luteum. Its function is the same as that of estradiol, which can promote and regulate the development of female accessory sex organs and promote the appearance of female accessory sex characteristics. Estrone is about one-tenth as active as estradiol, but three times more potent than estriol. Oral dose is more easily inactivated, so the oral dose is about five times more than the injection dose.

USES:

1. Biochemical research, estrogen drugs.

2. It is an intermediate for the synthesis of medical ethinylestradiol

3, mainly used for uterine dysplasia, menstrual disorders and menopause disorders. It is an intermediate for the synthesis of ethinylestradiol drugs. Can cause nausea, vomiting, dizziness and so on. Prolonged use can cause endometrial hyperplasia and bleeding.

4. It is the intermediate of no. 1 contraceptive medicine hormone ethinylestradiol.

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