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23111-00-4 Active Pharmaceutical Ingredients Nicotinamide Riboside Chloride NRC
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Detailed Product Description
| CAS No: | 23111-00-4 | Molecular Formula: | C11H15ClN2O5 |
|---|---|---|---|
| Molecular Weight: | 290.7002 | Category: | Medical Grade |
| Content: | 99% | Appearance: | White Powder |
| Packing: | 25KG/ Cardboard Drum | Application: | Intermediates, Important Applications In Preventing Stem Cell Senescence And Maintaining Stem Cell Function |
| High Light: | active pharma ingredients,pharmaceutical grade api intermediate |
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Nicotinamide Riboside Chloride(NRC)23111-00-4 Active Pharmaceutical Ingredients
Basic parameter:
1. Product name: Nicotinamideribosidechloride
2. Other names :NRC; NicotinamideRibosideChloride (NRC); NicotinamideribosidechlorideNR - CL;
Nicotinamideribosidechloride; 3 - Carbamoyl - 1 - beta - D - ribofuranosylpyridiniumchloride; 3 - carbamoyl - 1 - (2 r, 3 r, 4 s, 5 r) - 3, 4 - dihydroxy - 5 - (hydroxymethyl) tetrahydrofuran - 2 - yl) - iumchloride pyridin - 1; NR - CL; Nicotinamideribosechloride
3. CAS no. : 23111-00-4
4. Molecular formula: C11H15ClN2O5
5. Molecular weight: 290.7002
6. Level: medical grade
7. Content: 99%
8. Appearance: white powder
9. Packing: 25KG/ cardboard drum
10. Application: intermediates, important applications in preventing stem cell senescence and maintaining stem cell function
Structure:
USES:
Nicotinamide mononucleotide plays an important role in the energy generation of human cells, and it is involved in the synthesis of NAD (nicotinamide adenine dinucleotide, an important coenzyme of cell energy transformation) in cells.
Summary:
Niacinamide nucleoside is the precursor of nicotinamide adenine dinucleotide (NAD) and represents the source of vitamin B3. Recent studies have shown that new health benefits can be achieved by ingesting higher amounts of niacinamide nucleosides than those naturally found in foods. For example, niacinamide nucleosides have been involved in increasing tissue NAD concentration and inducing insulin sensitivity as well as enhancing deacetylase (sirtuin) function. Its ability to increase NAD production suggests that niacinamide nucleoside can also improve mitochondrial health, stimulate mitochondrial function and induce the generation of new mitochondria. Other studies using nicotinamide nucleosides in models of alzheimer's disease have shown that the molecule is biologically available to the brain and may provide neuroprotection by stimulating NAD synthesis in the brain (ibid.). In addition, the 2012 study observed that mice on a high-fat diet supplemented with niacinamide riboside gained 60 percent less weight than mice on the same high-fat diet without niacinamide riboside. Nicotinamide nucleoside chloride (3-aminoformyl-1 -[(2R, 3R, 4S5R)-3, 4-dihydroxy -5-(hydroxymethyl) oxyheterocyclic pentane -2-] -pyridine -1- onium chloride; Also known as 1-(joy-d-furan ribosyl) niacinamide chloride) is a known salt form of niacinamide nucleoside. Although there are useful properties of the niacinamide nucleoside and its chloride salts (e.g., in medicines or nutritional supplements), they usually require improvement.
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