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Melatonin 73-31-4 Cosmetic Raw Materials for Delay Aging And Improve Sleep
Product Details:
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Detailed Product Description
| CAS No: | 73-31-4 | Molecular Formula: | C13H16N2O2 |
|---|---|---|---|
| Molecular Weight: | 232.28 | EINECS No: | 200-797-7 |
| Melting Point: | 116.5-118 ° C | Boiling Point: | 374.44 ° C |
| Density: | 1.1099 | Index Of Refraction: | 1.6450 |
| Flash: | 9 ℃ | Storage Conditions: | -15°C |
| Solubility: | Soluble In Ethanolto At Further 50 Mg/ml. | Appearance: | White Or Almost White Crystalline Powder |
| High Light: | raw materials used in cosmetics,makeup raw materials |
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melatonin 73-31-4 cosmetic raw materials used to delay aging and improve sleep
Basic parameter:
1. Product name :Melatonine
2. Product alias :Melatonin(AS); Melatonine, N - (2 - (5 - Methoxyindol - 3 - yl) baton rouge) acetaMide. MELATONINEFORSYNTHESIS1G; MELATONINEFORSYNTHESIS5G; Melatonin0.25; MelatonineSynonymsN - (2 - (5 - methoxyindol - 3 - yl) baton rouge) acetamide. Melatoninsolution; N - ACETYL - 5 - METHOXYTRYPTAMINE
3. CAS no. : 73-31-4
4. Molecular formula: C13H16N2O2
5. Molecular weight: 232.28
6. EINECS no. : 200-797-7
7. Melting point: 116.5-118 ° C
8. Boiling point: 374.44 ° C
9. Density: 1.1099
10. Index of refraction: 1.6450
11. Flash: 9 ℃
12. Storage conditions: -15°C
13. Solubility: Soluble in ethanolto at further 50 mg/ml.
14. Appearance: white or almost white crystalline powder
Certificate of Analysis:
| Product Name |
Melatonin (N-Acetyl-5-Methoxytryptamine) |
Batch No. | 20200101 | |||
| CAS No. | 73-31-4 | Formula | C13H16N2O2 | |||
| MFG. Date | Jan 10,2020 | Exp Date | Jan 09,2022 | |||
| Quantity | 300kgs | Ref. Standard | Enterprise Standard | |||
| ITEMS | METHOD | SPECIFICATIONS | RESULTS | |||
| Description | Visual Inspection | Off-White to white crystalline powder | Conforms | |||
| Identification | IR | Conforms to reference | Conforms | |||
| Chromatographic | TLC | No secondary spot and identical Rf to reference | Conforms | |||
| Assay |
HPLC Melatonin HPLC Impurities Peak E |
≥99.0% Total≤1.0% Absent |
99.5% Not Detected Absent |
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| Sulphated Ash | USP | ≤0.1% | 0.04% | |||
| Heavy Metals | USP | ≤10ppm | ＜10ppm | |||
| Arsenic | USP | ≤1ppm | ＜1ppm | |||
| Loss on Drying | USP | ≤0.2% | 0.05% | |||
| Melting Point | USP | 117～119oC | 117～118 oC | |||
| Bulk Density | USP | g/ml | 0.44g/ml | |||
| Tap Density | USP | g/ml | 0.62g/ml | |||
| Particle Size | USP | 100% through 40 mesh | Conforms | |||
| Residual Solvents | ||||||
| Ethyl Acetate | USP | Absent | Absent | |||
| Acetic Acid | USP | Absent | Absent | |||
| Ethanol | USP | ≤50ppm | 200ppm | |||
| Microbiological Analysis | ||||||
| Total plate counts | USP | ≤1000cfu/g | ＜1000cfu/g | |||
| Yeast and Mold | USP | ≤100cfu/g | ＜100cfu/g | |||
| E.Coli | USP | Negative | Negative | |||
| Staphylococcus | USP | Negative | Negative | |||
| salmonella | USP | Negative | Negative | |||
Structure:
Main USES:
Anti-aging:
Free radicals may be produced by enzymatic and non-enzymatic reactions in the body. Free radicals are closely related to aging. The production and elimination of free radicals in the normal body are in a dynamic balance. Once this balance is broken, free radicals will cause damage to biological macromolecules such as lipids, proteins and nucleic acids, leading to the destruction of cell structure and the aging of the body. Melatonin protects cell structure, prevents DNA damage, and reduces the amount of peroxides in the body by scavenging free radicals, resisting oxidation, and inhibiting lipid peroxidation. Some studies have found that melatonin can protect up to 99 percent of DNA damage caused by safrol, a carcinogen that damages DNA by releasing free radicals, in a dose-response relationship. Melatonin has a significant antagonistic effect on tissue damage caused by peroxidation and free radicals produced by exogenous poisons such as paraquat. Melatonin can also reduce the content of LPO in the brain, and it ACTS on different areas of the brain, such as the cerebral cortex, cerebellum, hippocampus, hypothalamus, striatum, etc., which are basically the same, and all show a dose-dependent relationship. However, different strains of rats such as Sprague-Dawlay and Wistar rats had different sensitivity to melatonin.
Improved sleep:
It can shorten the waking time and sleep time before going to bed, and improve the sleep quality. The number of waking times in sleep is significantly reduced, the light sleep stage is short, the deep sleep stage is prolonged, and the wake-up threshold drops in the next morning. Has the strong adjustment time difference function. Mainly used for whitening and moisturizing cosmetics, also used in hair products. The biological function of melatonin, especially its health care function as a dietary supplement, has been extensively studied at home and abroad, which indicates that melatonin has many physiological functions, such as promoting sleep, regulating jet lag, anti-aging, regulating immunity and anti-tumor. The health care function of melatonin at home and abroad involves regulation of endocrine (inhibition of ovulation), protection of encephalitis virus infection, and reduction of its mortality after infection, the treatment of AIDS and cardiovascular protection.
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Contact Details
WuHan Dong Kang Yuan technology co., LTD
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Tel: 86-15377658509
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