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Ceftriaxone Sodium Ingredients Sterile Packaging High Content 99%

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Ceftriaxone Sodium Ingredients Sterile Packaging High Content 99%

Large Image : Ceftriaxone Sodium Ingredients Sterile Packaging High Content 99% Get Best Price

Product Details:

Place of Origin:	HUBEI
Brand Name:	DKY
Certification:	GMP
Model Number:	CP, USP ,EP

Payment & Shipping Terms:

Minimum Order Quantity:	5kg
Price:	240USD/KG
Packaging Details:	5kg aluminium cans
Delivery Time:	2days
Payment Terms:	T/T, Western Union, MoneyGram
Supply Ability:	5000KG

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Detailed Product Description

CAS:

74578-69-1

EINECS:

277-930-0

Packaging:

5kg Aluminium Cans

Content:

99%

High Light:

active pharma ingredients

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Ceftriaxone Sodium Ingredients Sterile Packaging High Content GMP Manufacturer Quality Assurance

Product Name: Ceftriaxone sodium

Synonyms: Ceftriaxone sodium crude product;CEFATRIAXONE;2,5,6-tetrahydro-2-methyl-5,6-dioxo-)(methoxyimino)acetyl)amino)-8-oxo-3-(((;4-triazin-3-yl)thio)methyl)-,sodiumsalt,hydrate(2:4:7)(6r-(6-alpha,7-2;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, disodium salt, [6R-[6α,7β(Z)]]-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3-[[(1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-1,2,4-triazin-3-yl)thio]methyl]-, disodium salt, (6R,7R)-;Ceftriaxone disodium;Longaceph

CAS: 74578-69-1

MF: C18H18N8O7S3

MW: 554.58

EINECS: 277-930-0

Ceftriaxone sodium Usage And Synthesis

Uses Ceftriaxone sodium is antibacteria.

Clinical Use Ceftriaxone sodium is a β-lactamase–resistantcephalosporin with an extremely long serum half-life.Once-daily dosing suffices for most indications. Two factorscontribute to the prolonged duration of action ofceftriaxone: high protein binding in the plasma and slowurinary excretion. Ceftriaxone is excreted in both the bileand the urine. Its urinary excretion is not affected byprobenecid. Despite its comparatively low volume ofdistribution, it reaches the cerebrospinal fluid in concentrationsthat are effective in meningitis.

Ceftriaxone contains a highly acidic heterocyclic systemon the 3-thiomethyl group. This unusual dioxotriazine ringsystem is believed to confer the unique pharmacokineticproperties of this agent. Ceftriaxone has been associatedwith sonographically detected “sludge,” or pseudolithiasis,in the gallbladder and common bile duct.

Ceftriaxone exhibits excellent broad-spectrum antibacterialactivity against both Gram-positive and Gram-negativeorganisms. It is highly resistant to most chromosomally andplasmid-mediated β-lactamases. The activity of ceftriaxoneagainst Enterobacter, Citrobacter, Serratia, indole-positiveProteus, and Pseudomonas spp. is particularly impressive. Itis also effective in the treatment of ampicillin-resistant gonorrheaand H. influenzae infections but generally less activethan cefotaxime against Gram-positive bacteria and B.fragilis.