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Phenacetin 62-44-2 Raw Material Relieve Heat And Pain
Product Details:
Payment & Shipping Terms:
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Detailed Product Description
| CAS No: | 62-44-2 | Molecular Formula: | C10H13NO2 |
|---|---|---|---|
| Molecular Weight: | 179.21600 | Appearance: | White Crystalline Powder |
| Density: | 1.099 G/cm3 | Melting Point: | 133-136 °C |
| Boiling Point: | 132 °C At 4mmHg | Index Of Refraction: | 1.505 (20ºC) |
| Water Solubility: | 0.076 G/100 ML | Stability: | Stable. Incompatible With Strong Oxidizing Agents, Strong Acids. |
| Refractive Index: | 1.571 | Solubility: | Insoluble In Water, Slightly Soluble In Ether, Slightly Soluble In Boiling Water, Soluble In Ethanol And Chloroform. |
| High Light: | pharma raw material,raw pharmaceutical materials |
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phenacetin 62-44-2 pharmaceutical raw material used to relieve heat and pain
Basic parameter:
1. Product name: phenacetin
2. Product alias: p-acetophenetidide; Acetamide, N - (4 - ethoxyphenyl) -; Achrocidin; P - ethoxyacetanilide; Codempiral;
3. CAS no. : 62-44-2
4. Molecular formula: C10H13NO2
5. Molecular weight: 179.21600
6. Appearance: white crystalline powder
7. Density: 1.099 g/cm3
8. Melting point: 133-136 °C(lit.)
9. Boiling point: 132 °C / 4mmHg
10. Index of refraction: 1.505 (20 C)
11. Water solubility: 0.076 g/100 mL
12. Stability: Stable. Incompatible with strong oxidizing agents, strong acids.
13. Refractive index: 1.571.
14. Solubility: insoluble in water, slightly soluble in ether, slightly soluble in boiling water, soluble in ethanol and chloroform.
Certificate of Analysis:
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Product Name |
Phenacetin |
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Batch No |
191025 |
Quantity |
500KG |
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Received Date |
2019/10/25 |
Date of Report |
2019/10/25 |
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Exp Date |
3 years |
Standard |
BP 2010 edition |
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Test Items |
Specification |
Test Results |
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Description |
Should comply with the standard | Pass | |
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Identification |
Should be positive reaction | Pass | |
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P-Phenetidine |
Brownish red 4# | Pass | |
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4-chloroacetanilide |
Should comply with standard | Pass | |
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Sulphated ash |
≤0.1% | 0.06% | |
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Melting point |
134℃ to 137℃ | 134℃ to 137℃ | |
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Appearance |
≥99% | 100.58% | |
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Conclusion |
Complies with BP2010 edition |
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Structure:
USES:
1. P-acetaminophenyl ether is used as organic synthesis raw material and drug intermediate.
2. Apis for scientific research.
3. Substrates of CYP1A2 and CYP2D6.
4. Antipyretic analgesic, used for the treatment of fever, headache, neuralgia, etc.
Product evaluation:
Antipyretic analgesic, used for the treatment of fever, headache, neuralgia, etc. Antipyretic effect is stronger than analgesic effect. Its potency is similar to that of aspirin, its effect is slow and lasting, and its toxicity is low. The results showed that this product and its metabolite acetaminophen had antipyretic effect. Because enzyme inhibitors prevent the conversion of phenacetin to acetaminophen, it still has a significant antipyretic effect. Therefore, the antipyretic effect after the product is not only produced by the active product acetaminophen. The mild analgesic effect of phenacetin can be generally maintained for 3-4 hours. Combined with salicylic acid, the analgesic effect is enhanced. Clinically, it is mainly used for antipyretic analgesia of small animals. This product is also a component of APC tablets.
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